8-(tert-Butyldimethylsilyloxy) 8-Hydroxy Efavirenz, Technical Grade CAS 1027042-31-4
| CAS No. | 1027042-31-4 |
| Molecular Formula | C20H23ClF3NO3Si |
| Molecular Weight | 445.94 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 8-(tert-Butyldimethylsilyloxy) 8-Hydroxy Efavirenz, Technical Grade is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
8-(tert-Butyldimethylsilyloxy) 8-Hydroxy Efavirenz, Technical Grade (CAS 1027042-31-4), molecular formula C20H23ClF3NO3Si and molecular weight 445.94 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 8-(tert-Butyldimethylsilyloxy) 8-Hydroxy Efavirenz, Technical Grade (C20H23ClF3NO3Si) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 445.94 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 8-(tert-Butyldimethylsilyloxy) 8-Hydroxy Efavirenz, Technical Grade under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H23ClF3NO3Si |
| Molecular Weight | 445.94 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related tert Standards
- 8-(tert-Butyldimethylsilyloxy) 8-Hydroxy Efavirenz-d4 (CAS 1185072-51-8)
- 2-(3-((tert-Butyldimethylsilyloxy)methyl)-pyrrolidin-1-yl)-6-fluoro-4-iodopyridine (CAS 1228665-82-4)
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Recommended Standards
- Crisaborole lmpurity 98 (CAS CATO-C4X-202198)
- 2-phenoxyethyl chloroformate (CAS 34743-87-8)
- Crisaborole impurity 116 (CAS CATO-C4X-2021116)
- Methyl 2-[({4-[(4-chlorophenyl)sulfanyl]-3-nitrophenyl}methyl)sulfanyl]benzoate (CAS 477869-66-2)
- 1,3-Bis((R)-1-phenylethyl)-1,3,2-diazaphospholidine 2-oxide (CAS 1449218-80-7)
- 4-Bromo-1-(isopentyloxy)-2-methylbenzene (CAS 1409185-73-4)
- N-(4-bromobenzyl)-1-(pyridin-3-yl)methanamine (CAS 510723-60-1)
- 3-(1,3-Dipropylpyrrolidin-3-yl)phenyl acetate (CAS 69745-67-1)
- 2-(Boc-amino)-1-(1-methyl-2-imidazolyl)ethanone (CAS 876392-21-1)
- [5-(Benzyloxy)-2-methoxyphenyl]boronic acid (CAS 2051586-00-4)
- BTA-2 (CAS 10205-62-6)
- (S)-2-Amino-1-(4-((isopropyl(methyl)amino)methyl)piperidin-1-yl)-3-methylbutan-1-one (CAS 1307654-91-6)
- 2-Chloro-3-methylbutanoyl chloride (CAS 35383-59-6)
- Peptide 74 (H-8545.0500) (CAS 132116-39-3)
Why CATO?
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