2-(Isothiazol-4-yl)acetic acid CAS 10271-93-9
| CAS No. | 10271-93-9 |
| Molecular Formula | C5H5NO2S |
| Molecular Weight | 143.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2-(Isothiazol-4-yl)acetic acid (CAS 10271-93-9), a certified reference material (molecular formula C5H5NO2S, MW 143.16 g/mol) for analytical method development and quality control.
2-(Isothiazol-4-yl)acetic acid (C5H5NO2S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(Isothiazol-4-yl)acetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H5NO2S |
| Molecular Weight | 143.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1959 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Isothiazol Standards
- 2-(Isothiazol-5-yl)acetic acid (CAS 10271-84-8)
- 2-(Isothiazol-3-yl)acetic acid (CAS 10271-91-7)
- N-(Isothiazol-3-ylmethyl)ethanamine (CAS 952195-17-4)
- 1-(3-Methyl-isothiazol-4-yl)-ethanone (CAS 23031-80-3)
- 1-(3-Methyl-isothiazol-5-yl)-ethanone (CAS 90724-49-5)
- 1-(Isothiazol-5-yl)ethan-1-ol (CAS 1285260-78-7)
- 1-(Isothiazol-3-yl)ethan-1-ol (CAS 1614825-80-7)
- (5-Methyl-isothiazol-3-yl)-methanol (CAS 1803598-19-7)
Recommended Standards
- 5-Methylisothiazole-3-carboxylic acid (CAS 110632-59-2)
- 5-Methylisothiazole-4-carboxylic acid (CAS 1125409-67-7)
- Pyridine-4-sulfinic acid (CAS 101084-78-0)
- 5-Aminothiophene-3-carboxylic acid (CAS 116539-01-6)
- tert-Butyl 4-(4-{[(2-Hydroxy-1,1-dimethylethyl)amino]carbonyl}-2-oxopyrrolidin-1-yl)piperidine-1-carboxylate (CAS 1221278-48-3)
- 4,4-Difluoro-1-[(3-fluorophenyl)methyl]cyclohexan-1-amine hydrochloride (CAS 1389315-20-1)
- 2,3-Diaminobenzaldehyde (CAS 109203-48-7)
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- Rivastigmine Impurity 15 (CAS 71607-31-3(free base))
- 4-(2-Methoxy-5-methylphenyl)thiazol-2-amine hydrochloride (CAS 1177334-96-1)
- 4-Ethoxy-3-ethylbenzo[d]thiazol-2(3H)-imine 4-methylbenzenesulfonate (CAS 2034156-80-2)
- N-(2,4-Difluorophenyl)-2-[4-(5-methyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidin-2-yl]acetamide (CAS 1775402-96-4)
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