2-(Difluoromethyl)-1-fluoro-3-(trifluoromethyl)benzene CAS 1027231-61-3
| CAS No. | 1027231-61-3 |
| Molecular Formula | C8H4F6 |
| Molecular Weight | 214.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(Difluoromethyl)-1-fluoro-3-(trifluoromethyl)benzene is closely related to fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-(Difluoromethyl)-1-fluoro-3-(trifluoromethyl)benzene (CAS 1027231-61-3), molecular formula C8H4F6 and molecular weight 214.11 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-(Difluoromethyl)-1-fluoro-3-(trifluoromethyl)benzene (C8H4F6) contains fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 214.11 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(Difluoromethyl)-1-fluoro-3-(trifluoromethyl)benzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H4F6 |
| Molecular Weight | 214.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
Related Difluoromethyl Standards
- 1-(Difluoromethyl)-3-fluoro-5-(trifluoromethyl)benzene (CAS 1161362-03-3)
- 2-(Difluoromethyl)-1-fluoro-4-(trifluoromethyl)benzene (CAS 1214334-37-8)
- 1-(Difluoromethyl)-4-fluoro-2-(trifluoromethyl)benzene (CAS 1214334-45-8)
- 2-(Difluoromethyl)-4-fluoro-1-(trifluoromethyl)benzene (CAS 1214358-19-6)
- 4-(Difluoromethyl)-1-fluoro-2-(trifluoromethyl)benzene (CAS 1214364-78-9)
- 1-(Difluoromethyl)-2-fluoro-4-(trifluoromethyl)benzene (CAS 1214364-84-7)
- 1-(Difluoromethyl)-2-fluoro-3-(trifluoromethyl)benzene (CAS 1214372-93-6)
- 4-(Difluoromethyl)-2-fluoro-1-(trifluoromethyl)benzene (CAS 1214383-47-7)
Recommended Standards
- Pyridine,2-(bromomethyl)-6-propyl (CAS 442910-39-6)
- 1,2,3-Trifluoro-4-(2,2,2-trifluoroethyl)benzene (CAS 1099597-23-5)
- N-Ethyl-4-bromobenzylamine (CAS 856795-95-4)
- 1,2,4-Trifluoro-5-(2,2,2-trifluoroethyl)-benzene 1099597-26-8 8666AC C8H4F6 (CAS 1099597-26-8)
- N,N-dimethyl-4-(m-tolyldiazenyl)aniline (CAS 55-80-1)
- (4-Chloro-2-fluoro-3-methoxyphenyl)boronic Acid (CAS 944129-07-1)
- 1-(2-Iodophenyl)-N-methylmethanamine (CAS 113258-86-9)
- N-(3-Amino-2-methylphenyl)-2-(2-methoxyphenoxy)-propanamide (CAS 1020056-62-5)
- 1-Chloro-2-(ethoxymethyl)-4-nitrobenzene (CAS 1097789-94-0)
- 2-(Aminomethyl)-4-(difluoromethyl)-5-methyl-3-nitropyridine (CAS 1805074-52-5)
- 5-[(5-Amino-1,3,4-thiadiazol-2-yl)methyl]-1,3,4-thiadiazol-2-ylamine oxalate (CAS 1177328-21-0)
- 2,3,3-Trimethylcyclobutan-1-one (CAS 28290-01-9)
- Boc-DL-Trp-OH (CAS 112525-72-1)
- Insulin Degludec Impurity 6 (CAS CATO-C4X-21576)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com