3-(4-Methylpiperazin-1-yl)-1H-indazol-5-amine CAS 1027258-20-3
| CAS No. | 1027258-20-3 |
| Molecular Formula | C12H17N5 |
| Molecular Weight | 231.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(4-Methylpiperazin-1-yl)-1H-indazol-5-amine (CAS 1027258-20-3), molecular formula C12H17N5 and molecular weight 231.30 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, 3-(4-Methylpiperazin-1-yl)-1H-indazol-5-amine is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 231.30 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H17N5 |
| Molecular Weight | 231.30 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 5 |
Related Methylpiperazin Standards
- 1-((4-Methylpiperazin-1-yl)methyl)-1H-benzo[d][1,2,3]triazole (CAS 19212-84-1)
- 2-(4-Methylpiperazin-1-yl)-1H-benzo[d]imidazol-5-amine (CAS 832102-59-7)
- 2-((4-Methylpiperazin-1-yl)methyl)indoline (CAS 1502041-38-4)
- 7-(4-Methylpiperazin-1-yl)-1,2,3,4-tetrahydroquinoline (CAS 216059-76-6)
- 6-(4-Methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-ol (CAS 1446786-35-1)
- 2-((3-Methylpiperazin-1-yl)methyl)-1h-benzo[d]imidazole (CAS 1087608-37-4)
- (2E)-1-(2-Methylpiperazin-1-yl)-3-phenylprop-2-en-1-one (CAS 1240590-90-2)
- (2E)-1-(3-Methylpiperazin-1-yl)-3-phenylprop-2-en-1-one (CAS 1240590-99-1)
Recommended Standards
- 7-Diethylamino-4-methylcoumarin (CAS 91-44-1)
- N-Cyclohexyl-9-methyl-9H-purin-6-amine (CAS 109292-93-5)
- Boc-D-Tle-OH (CAS 124655-17-0)
- (S)-5-Methyl-4-(3-methylpiperazin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine (CAS 1116570-96-7)
- 4,4'-(9,9-Dimethyl-9H-fluorene-2,7-diyl)dipyridine (CAS 1217980-22-7)
- 5-Bromo-2H-benzo[e][1,2,4]thiadiazin-3(4H)-one 1,1-dioxide (CAS 155983-98-5)
- 1-(3,5,5,6,8,8-Hexamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethan-1-one (CAS 1506-02-1)
- 3-(3,5-Dimethylisoxazol-4-yl)propan-1-ol (CAS 129975-10-6)
- Ethyl 4-(2-((5-cyano-4-(trifluoromethyl)-[2,4'-bipyridin]-6-yl)thio)acetamido)benzoate (CAS 625378-12-3)
- 4-(3,4-Difluorobenzylidene)-2-methyloxazol-5(4H)-one (CAS 182009-50-3)
- 4-(5-Vinylpyridin-2-yl)morpholine (CAS 223556-21-6)
- 2-(2-(Chloromethyl)-6,7-dimethoxy-4-oxoquinazolin-3(4h)-yl)acetonitrile (CAS 743441-89-6)
- Potassium (2-bromophenylsulfonamido)methyltrifluoroborate (CAS 1286686-28-9)
- Semaglutide impurity 267 (CAS CATO-C4X-2226267)
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