(3,3-Difluoropyrrolidin-2-yl)methanol CAS 1027519-80-7
| CAS No. | 1027519-80-7 |
| Molecular Formula | C5H9F2NO |
| Molecular Weight | 137.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (3,3-Difluoropyrrolidin-2-yl)methanol is closely related to an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(3,3-Difluoropyrrolidin-2-yl)methanol (CAS 1027519-80-7) is a high-purity analytical reference standard with the molecular formula C5H9F2NO and a molecular weight of 137.13 g/mol.
Structurally, (3,3-Difluoropyrrolidin-2-yl)methanol (C5H9F2NO) contains an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 1.0, corresponding to approximately 1 ring(s) or double-bond equivalent(s). With a molecular weight of 137.13 g/mol, it falls into the low-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (3,3-Difluoropyrrolidin-2-yl)methanol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H9F2NO |
| Molecular Weight | 137.13 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoropyrrolidin Standards
- [(2R)-4,4-Difluoropyrrolidin-2-yl]methanol (CAS 1315691-45-2)
- (4,4-Difluoropyrrolidin-2-yl)methanol (CAS 1334488-61-7)
- (4,4-Difluoropyrrolidin-3-yl)methanol (CAS 763060-99-7)
- [(2S)-4,4-Difluoropyrrolidin-2-yl]methanol (CAS 771473-90-6)
- (S)-(4,4-Difluoropyrrolidin-2-yl)methanamine (CAS 1821494-02-3)
- (R)-(4,4-Difluoropyrrolidin-2-yl)methanamine (CAS 1821494-05-6)
- 2-(3,3-Difluoropyrrolidin-1-yl)ethan-1-ol (CAS 950662-61-0)
- (R)-4,4-difluoropyrrolidin-3-ol (CAS 1433946-75-8)
Recommended Standards
- Methotrexate Impurity 27 (CAS 64620-79-7)
- 4,4-Difluoropiperidin-3-ol (CAS 1187087-19-9)
- SKF-97541 (CAS 127729-35-5)
- 3-(1,1-difluoroethyl)-1H-1,2,4-triazole (CAS 1202645-15-5)
- 5-Nitroquinoxaline (CAS 18514-76-6)
- 3-(5-Bromo-2-methoxyphenyl)propan-1-ol (CAS 33538-79-3)
- 6-bromo-1,2,3,4-tetrahydronaphthalene-2-sulfonyl chloride (CAS 1342867-76-8)
- tert-butyl 4-(bromomethyl)-4-fluoropiperidine-1-carboxylate (CAS 1207176-24-6)
- ethyl 5-chloro-1H-1,2,4-triazole-3-carboxylate (CAS 774608-88-7)
- 3-(Methylsulfonyl)thiophene-2-carbaldehyde (CAS 2092396-88-6)
- Tirzepatide Impurity 10 (CAS CATO-C4X-324010)
- 6-((Tert-butoxycarbonyl)amino)bicyclo[3.1.1]Heptane-3-carboxylic acid (CAS 1334146-33-6)
- (1-(2,2,2-Trifluoroethyl)pyrrolidin-2-yl)methanol (CAS 1250714-14-7)
- Semaglutide impurity 29 (CAS 1188328-22-4)
Why CATO?
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