(E)-3-(3,5-Bis(trifluoromethyl)phenyl)acrylonitrile CAS 1027717-63-0
| CAS No. | 1027717-63-0 |
| Molecular Formula | C11H5F6N |
| Molecular Weight | 265.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (E)-3-(3,5-Bis(trifluoromethyl)phenyl)acrylonitrile.
(E)-3-(3,5-Bis(trifluoromethyl)phenyl)acrylonitrile (CAS 1027717-63-0), molecular formula C11H5F6N and molecular weight 265.15 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, (E)-3-(3,5-Bis(trifluoromethyl)phenyl)acrylonitrile is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 265.15 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H5F6N |
| Molecular Weight | 265.15 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 2-(3-Bromophenyl)-2-(pyrrolidin-1-yl)acetonitrile (CAS 1017466-79-3)
- 2-Bromo-N-((1-methyl-1h-pyrrol-2-yl)methyl)aniline (CAS 1039810-31-5)
- Methyl 4-(bromomethyl)-3-methoxybenzoate 3-methoxy-4-bromomethylbenzoic acid methyl ester 4-bromomethyl-3-methoxy-benzoic acid methyl ester methyl 3-methoxy-4-bromomethylbenzoate 4-(bromomethyl)-3-methoxybenzoate 3-Methoxy-4-(bromomethyl)benzoic acid methyl ester Methyl 4-(Bromomethyl)-m-anisate 70264-94-7 (CAS 70264-94-7)
- 4-Bromo-N-((1-methyl-1h-pyrrol-2-yl)methyl)aniline (CAS 1040074-32-5)
- 2,4-Dichlorophenyl Acetic Acid (CAS 19719-28-9)
- 1-(2-Ethoxyphenyl)butan-1-one (CAS 342422-36-0)
- Tert-butyl 3,4,4a,5,6,7-hexahydro-1,5-naphthyridine-1(2H)-carboxylate (CAS 2716849-50-0)
- 4-Bromo-3-chlorobenzo[d]isoxazole (CAS 1260751-76-5)
- 2-[(4-phenylphenyl)formamido]acetic acid (CAS 75446-59-2)
- Fmoc-N-Lys-(PEG12-biotin)-OH-(acid) (CAS 1334172-65-4)
- Flutamide EP Impurity C (CAS 13312-12-4)
- Cyclobutyl(2-(trifluoromethyl)phenyl)methanone (CAS 53342-41-9)
- Methyl 3-Mercaptobenzoate (CAS 72886-42-1)
- Insulin Degludec Impurity 26 (CAS CATO-C4X-215726)
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