1,2,3,4-Tetrahydroisoquinolin-5-ol hydrochloride CAS 102879-34-5

Purity 97%+In StockPharmaceutical Standards
CAS No.102879-34-5
Molecular FormulaC9H11NO
Molecular WeightN/A
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1,2,3,4-Tetrahydroisoquinolin-5-ol hydrochloride CAS 102879-34-5 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1,2,3,4-Tetrahydroisoquinolin-5-ol hydrochloride.

1,2,3,4-Tetrahydroisoquinolin-5-ol hydrochloride (CAS 102879-34-5), molecular formula C9H11NOHCl and molecular weight 185.65 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 1,2,3,4-Tetrahydroisoquinolin-5-ol hydrochloride (C9H11NOHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1,2,3,4-Tetrahydroisoquinolin-5-ol hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC9H11NO HCl
Molecular Weight185.65 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1986
Halogen ContentCl-containing
Nitrogen Atoms1

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