6-Hydroxy-1,4-benzodioxane CAS 10288-72-9
| CAS No. | 10288-72-9 |
| Molecular Formula | C8H8O3 |
| Molecular Weight | 152.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
6-Hydroxy-1,4-benzodioxane (CAS 10288-72-9), molecular formula C8H8O3 and molecular weight 152.15 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 6-Hydroxy-1,4-benzodioxane (C8H8O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H8O3 |
| Molecular Weight | 152.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
Related Hydroxy Standards
- 3-Hydroxy-2-methyl-d3-benzoic Acid (CAS 1020719-51-0)
- 3-Hydroxy-N-methylpicolinamide (CAS 1196-30-1)
- 2-Hydroxy-4-(hydroxymethyl)benzaldehyde (CAS 156605-23-1)
- 2-Hydroxy-5-methylnicotinamide (CAS 1822892-18-1)
- 4-hydroxy-2-methoxybenzaldehyde (CAS 18278-34-7)
- 3-Hydroxy-5-methylpicolinamide (CAS 1849298-65-2)
- 1-Acetyl-4-hydroxy-2,5-dihydro-1H-pyrrole-3-carbonitrile (CAS 18721-38-5)
- 5-Hydroxy-2-methylnicotinamide (CAS 1935228-87-7)
Recommended Standards
- 2,3-Dihydro-1,4-benzodioxin-5-ol (CAS 10288-36-5)
- 2-Amino-5-methylisonicotinic acid (CAS 1033203-35-8)
- 4-Amino-N-methylpyrimidine-5-carboxamide (CAS 102818-44-0)
- 3-Methylpyrazine-2-carbohydrazide (CAS 104893-68-7)
- (2-((4-Aminobutyl)amino)-2-oxoethyl)phosphonic acid (CAS 67023-07-8)
- [(1R,6R)-6-(hydroxymethyl)cyclohex-3-en-1-yl]methanol (CAS 15679-28-4)
- 3-(Difluoromethyl)-8-methoxycinnoline-6-carboxylic acid (CAS 2721375-69-3)
- 1,1-Dimethoxy-2-nitroethane (CAS 69425-53-2)
- 2-((1R,2S)-2-(4-methoxyphenyl)cyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2102308-73-4)
- 1-(2-(Diethylamino)ethyl)-5-(4-ethylphenyl)-4-(3-fluoro-4-methoxybenzoyl)-3-hydroxy-1H-pyrrol-2(5H)-one (CAS 618074-93-4)
- 4-(tert-Butyl)-3-hydroxybenzaldehyde (CAS 532966-59-9)
- 3-Cyclopropoxy-2-(dimethylamino)-N,N-dimethylbenzamide (CAS 1243467-38-0)
- 1-(4-Bromobenzyl)-1-(2-hydroxyhexyl)-4-phenylpiperidin-1-ium bromide (CAS 1025707-79-2)
- Staphylococcus Aureus Protein A (SpA)-Derived Peptide (H-2228.0005) (CAS 144979-26-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com