7,8-Difluorochroman CAS 1029476-87-6
| CAS No. | 1029476-87-6 |
| Molecular Formula | C9H8F2O |
| Molecular Weight | 170.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 7,8-Difluorochroman.
7,8-Difluorochroman (CAS 1029476-87-6), molecular formula C9H8F2O and molecular weight 170.16 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 7,8-Difluorochroman (C9H8F2O) is characterized by a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 7,8-Difluorochroman meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H8F2O |
| Molecular Weight | 170.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
Related Difluorochroman Standards
- 5,8-Difluorochroman (CAS 1522390-97-1)
- 5,7-Difluorochroman (CAS 1541675-72-2)
- 6,7-Difluorochroman-4-one (CAS 1092349-93-3)
- 5,6-Difluorochroman-4-one (CAS 1273595-87-1)
- 5,8-Difluorochroman-4-one (CAS 942196-01-2)
- 6,8-Difluorochroman-4-one (CAS 259655-01-1)
- 7,8-Difluorochroman-4-one (CAS 890840-90-1)
- 5,7-Difluorochroman-4-one (CAS 844648-22-2)
Recommended Standards
- (2,6-Difluorophenyl)acetone (CAS 101712-20-3)
- 3-(1,1-Difluoroethyl)benzaldehyde (CAS 1032527-37-9)
- 1-(2,3-Difluorophenyl)propan-2-one (CAS 101712-19-0)
- (e)-3-(2,3-Difluorophenyl)prop-2-en-1-ol (CAS 1033010-15-9)
- 4-(Dipropylamino)-N-(5-phenyl-1,3,4-oxadiazol-2-yl)butanamide (CAS 89758-26-9)
- 2-(Chloromethyl)-6-(difluoromethyl)-3-fluoro-4-iodopyridine (CAS 1805578-21-5)
- Methyl 7-bromo-4-hydroxy-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate (CAS 942152-80-9)
- 3-Amino-2-hydroxy-N,N,6-trimethylbenzamide (CAS 654683-53-1)
- (2-Fluoro-3-(4-methylpiperidine-1-carbonyl)phenyl)boronic acid (CAS 2096334-32-4)
- o-(Quinolin-4-ylmethyl)hydroxylamine (CAS 198558-11-1)
- (S)-3-(Pyridin-4-yl)morpholine (CAS 1213126-61-4)
- 3-(2-Chloroethyl)-5-fluoropyridine hydrochloride (CAS 2137895-55-5)
- 3-((4-Benzylpiperazin-1-yl)methyl)benzonitrile (CAS 940264-81-3)
- Semaglutide impurity 01 (CAS 1998701-31-7)
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