5-(3-Fluoro-4-methoxyphenyl)-1H-pyrazol-3-amine hydrochloride CAS 1031793-29-9

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(3-Fluoro-4-methoxyphenyl)-1H-pyrazol-3-amine hydrochloride.

5-(3-Fluoro-4-methoxyphenyl)-1H-pyrazol-3-amine hydrochloride (CAS 1031793-29-9) is a high-purity analytical reference standard with the molecular formula C10H10FN3OHCl and a molecular weight of 243.67 g/mol.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 5-(3-Fluoro-4-methoxyphenyl)-1H-pyrazol-3-amine hydrochloride is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 243.67 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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