1-(3-Chloro-4-methylphenyl)imidazolidin-2-one CAS 1031927-20-4

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(3-Chloro-4-methylphenyl)imidazolidin-2-one.

1-(3-Chloro-4-methylphenyl)imidazolidin-2-one (CAS 1031927-20-4) is a high-purity analytical reference standard with the molecular formula C10H11ClN2O and a molecular weight of 210.66 g/mol.

1-(3-Chloro-4-methylphenyl)imidazolidin-2-one (C10H11ClN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1-(3-Chloro-4-methylphenyl)imidazolidin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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