Diethyl 2-((6-bromo-2-chloroquinolin-3-yl)methylene)malonate CAS 1031928-81-0
| CAS No. | 1031928-81-0 |
| Molecular Formula | C17H15BrClNO4 |
| Molecular Weight | 412.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Diethyl 2-((6-bromo-2-chloroquinolin-3-yl)methylene)malonate (CAS 1031928-81-0), a certified reference material (molecular formula C17H15BrClNO4, MW 412.66 g/mol) for analytical method development and quality control.
Diethyl 2-((6-bromo-2-chloroquinolin-3-yl)methylene)malonate (C17H15BrClNO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Diethyl 2-((6-bromo-2-chloroquinolin-3-yl)methylene)malonate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H15BrClNO4 |
| Molecular Weight | 412.66 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Diethyl Standards
- Diethyl 2-((7-bromo-2-chloroquinolin-3-yl)methylene)malonate (CAS 1031928-83-2)
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- Diethyl ((triphenyl-l5-phosphaneylidene)methyl)phosphonate (CAS 183204-00-4)
- Diethyl (((3,4,5-trimethoxyphenyl)seleninyl)methyl)phosphonate (CAS 2485020-66-2)
- Diethyl 3,3′,4,4′-benzophenonetetracarboxylate (CAS 51018-94-1)
- 1,3-Diethyl 2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}-2-acetamidopropanedioate (CAS 306976-51-2)
- Diethyl 1-(4-(methylthio)phenyl)-5-phenyl-1H-pyrazole-3,4-dicarboxylate (CAS 96722-83-7)
- Diethyl 2-(3,5-dioxo-1,2-diphenylpyrazolidin-4-yl)malonate (CAS 6139-70-4)
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- 5-Methylpyrazine-2-carboxamidine (CAS 725234-33-3)
- N-benzyl-N-ethyl-4-nitrobenzamide (CAS 349396-05-0)
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