6-Chloro-1-methylquinazoline-2,4(1H,3H)-dione CAS 10320-59-9
| CAS No. | 10320-59-9 |
| Molecular Formula | C9H7ClN2O2 |
| Molecular Weight | 210.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-Chloro-1-methylquinazoline-2,4(1H,3H)-dione (C9H7ClN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
6-Chloro-1-methylquinazoline-2,4(1H,3H)-dione (CAS 10320-59-9), molecular formula C9H7ClN2O2 and molecular weight 210.62 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-Chloro-1-methylquinazoline-2,4(1H,3H)-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H7ClN2O2 |
| Molecular Weight | 210.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
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Recommended Standards
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- 3-Chloro-6-methoxy-1H-[1,5]naphthyridin-4-one (CAS 1073495-87-0)
- 1-((4-Chlorophenyl)sulfonyl)-2-methyl-4,5-dihydro-1H-imidazole (CAS 181481-30-1)
- 4-Bromo-2-fluorobenzo[d]oxazole (CAS 1804470-24-3)
- (2R)-4-[(tert-butoxy)carbonyl]-1,4-oxazepane-2-carboxylic Acid (CAS 1273566-86-1)
- 3-[(2-PHenylquinolin-4-yl)carbonyl]-1-vinylpyrrolidin-2-one (CAS 910442-92-1)
- 4-(tert-Butyl)-2-(methylsulfonyl)pyrimidine (CAS 1378259-39-2)
- Aspartame EP Impurity B (CAS 13433-09-5)
- 1-Isopropylpiperidin-3-ol (CAS 3554-62-9)
- (3Z)-3-{[(3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)amino]methylidene}-1-(pyrimidin-2-yl)pyrrolidin-2-one (CAS 338954-33-9)
- 2-Methoxy-6-methylbenzoic Acid (CAS 6161-65-5)
- Tirzepatide Impurity 12 (CAS CATO-C4X-324012)
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