Ethyl 2,4-dichloro-5-fluorobenzoate CAS 103318-75-8
| CAS No. | 103318-75-8 |
| Molecular Formula | C9H7Cl2FO2 |
| Molecular Weight | 237.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Ethyl 2,4-dichloro-5-fluorobenzoate (CAS 103318-75-8), molecular formula C9H7Cl2FO2 and molecular weight 237.06 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Ethyl 2,4-dichloro-5-fluorobenzoate (C9H7Cl2FO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Ethyl 2,4-dichloro-5-fluorobenzoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H7Cl2FO2 |
| Molecular Weight | 237.06 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F/Cl-containing |
Related Ethyl Standards
- Ethyl 3,5-dichloro-4-fluorobenzoate (CAS 115551-95-6)
- Ethyl 3,6-dichloro-2-fluorobenzoate (CAS 1214329-21-1)
- Ethyl 2,3-dichloro-6-fluorobenzoate (CAS 1214332-56-5)
- Ethyl 2,6-dichloro-3-fluorobenzoate (CAS 1214362-96-5)
- Ethyl 4,5-dichloro-2-fluorobenzoate (CAS 1214375-94-6)
- Ethyl 3,5-dichloro-2-fluorobenzoate (CAS 1520350-87-1)
- 2-(2,4-Dichloro-5-fluorophenyl)propanoic acid (CAS 1540880-32-7)
- Ethyl 2,4-dichloro-3-fluorobenzoate (CAS 1803718-57-1)
Recommended Standards
- 3-Chloro-4-ethoxy-5-fluorobenzoyl chloride (CAS 1017778-76-5)
- 3-(Aminomethyl)-7-(3-hydroxypropoxy)benzo[c][1,2]oxaborol-1(3H)-ol (CAS 1093643-33-4)
- 2-((4-Bromo-1-methyl-1H-pyrazol-5-yl)methylene)malononitrile (CAS 1005672-95-6)
- 8-Bromoquinoxaline-5-carbaldehyde (CAS 2101944-50-5)
- tert-Butyl cyclopropylsulfonylcarbamate (CAS 681808-26-4)
- 1-((Trifluoromethyl)thio)pyrrolidine-2,5-dione (CAS 183267-04-1)
- Methyl 6-(3-Methoxyphenyl)nicotinate (CAS 869985-47-7)
- 3-Bromo-5-(1h-pyrrol-1-yl)pyridine (CAS 1215911-30-0)
- Triethyl orthoacetate-d (CAS 97419-13-1)
- Ethyl 3-(5-nitrofuran-2-yl)acrylimidate (CAS 5315-29-7)
- benzothiophene-6-carboxylic acid (CAS 6179-26-6)
- 3-Cyano-2-fluorobenzeneboronic acid pinacol ester, 97% (CAS 1218791-15-1)
- Fenoprofen Ethyl Ester (CAS 32929-74-1)
- Semaglutide impurity 275 (CAS CATO-C4X-2226275)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com