(3R,4S)-(3-Boc-amino)-4-fluoropyrrolidine CAS 1033718-91-0
| CAS No. | 1033718-91-0 |
| Molecular Formula | C9H17FN2O2 |
| Molecular Weight | 204.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(3R,4S)-(3-Boc-amino)-4-fluoropyrrolidine (CAS 1033718-91-0), molecular formula C9H17FN2O2 and molecular weight 204.24 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (3R,4S)-(3-Boc-amino)-4-fluoropyrrolidine (C9H17FN2O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (3R,4S)-(3-Boc-amino)-4-fluoropyrrolidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H17FN2O2 |
| Molecular Weight | 204.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- tert-Butyl ((3S,4R)-4-fluoropyrrolidin-3-yl)carbamate (CAS 1033718-89-6)
- 2-Fluoro-4-(piperidin-4-yl)benzonitrile (CAS 1035264-55-1)
- tert-Butyl (3R,4S)-3-amino-4-fluoropyrrolidine-1-carboxylate (CAS 1009075-48-2)
- 8-Fluoro-2,3,4,9-tetrahydro-1H-carbazol-1-amine (CAS 1038264-02-6)
- 1H-Pyrrolo[2,3-c]pyridin-5-amine (CAS 174610-12-9)
- N-[(1S)-1-[2-(Cyclopropylamino)-1-hydroxy-2-oxoethyl]butyl]carbamic Acid Benzyl Ester (CAS 402959-34-6)
- 2-(1,1-Difluoroethyl)-1,3,5-trifluorobenzene (CAS 1138445-25-6)
- 6321-23-9 4-Methylcyclohexylamine Cyclohexanamine, 4-methyl- 4-Methylcyclohexylamine, mixed isomers Cyclohexylamine, 4-methyl- EINECS 228-673-8 p-Methylcyclohexylamine NSC 32387 (CAS 6321-23-9)
- n-[2-chloro-5-(trifluoromethyl)phenyl]-3-oxobutanamide (CAS 585-97-7)
- 6-Amino-5-methyl-2-morpholinopyrimidin-4(3h)-one (CAS 1342905-77-4)
- 5-(5-(Pyrrolidin-1-ylsulfonyl)furan-2-yl)-3-(o-tolyl)-1,2,4-oxadiazole (CAS 1207009-88-8)
- 1-(4-Fluorobenzyl)-3-((2-fluorobenzyl)oxy)imidazolidine-2,4,5-trione (CAS 320422-93-3)
- 1-(1-(Aminomethyl)cyclobutyl)butan-1-ol (CAS 1541054-56-1)
- Semaglutide impurity 61 (CAS CATO-C4X-222661)
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