5-Amino-1-(3,5-difluorophenyl)-1H-pyrazole-4-carboxylic acid CAS 1034142-07-8
| CAS No. | 1034142-07-8 |
| Molecular Formula | C10H7F2N3O2 |
| Molecular Weight | 239.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 5-Amino-1-(3,5-difluorophenyl)-1H-pyrazole-4-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
5-Amino-1-(3,5-difluorophenyl)-1H-pyrazole-4-carboxylic acid (CAS 1034142-07-8), molecular formula C10H7F2N3O2 and molecular weight 239.18 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 5-Amino-1-(3,5-difluorophenyl)-1H-pyrazole-4-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 239.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H7F2N3O2 |
| Molecular Weight | 239.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Amino Standards
- 5-Amino-1-(2,4-difluorophenyl)-1h-pyrazole-4-carboxylic acid (CAS 918405-21-7)
- 1-(4-Amino-1,2,5-oxadiazol-3-yl)-5-(methoxymethyl)-1H-1,2,3-triazole-4-carboxamide (CAS 312267-70-2)
- (S)-2-amino-2-(3-fluoro-4-(trifluoromethoxy)phenyl)ethan-1-ol (CAS 1213402-51-7)
- (R)-2-amino-2-(3-fluoro-4-(trifluoromethoxy)phenyl)ethan-1-ol (CAS 1213874-86-2)
- 6-Amino-5-(difluoromethyl)-4-hydroxypyridine-2-sulfonamide (CAS 1804514-46-2)
- 6-Amino-4-(difluoromethyl)-5-hydroxypyridine-2-sulfonamide (CAS 1804514-53-1)
- 2-Amino-5-(difluoromethyl)-3-hydroxypyridine-4-sulfonamide (CAS 1805013-06-2)
- 4-Amino-5-(difluoromethyl)-6-hydroxypyridine-2-sulfonamide (CAS 1805138-76-4)
Recommended Standards
- 3-Difluoromethyl-4-nitro-5-phenylpyrazole (CAS 1029650-43-8)
- 1-(3,5-Difluorophenyl)-5-methyl-1h-1,2,3-triazole-4-carboxylic acid (CAS 1094411-40-1)
- Sodium 4-methoxy-3-nitrobenzenesulfinate (CAS 101241-42-3)
- 8-nitro-3,4-dihydro-2H-1,5-benzodioxepine-7-carboxylic acid (CAS 1094424-70-0)
- 7-Methoxyisoquinolin-4-amine (CAS 98263-36-6)
- N-Ethyl-N-(imidazo[1,2-a]pyridin-3-ylmethyl)-3-methoxy-1-methyl-1H-pyrazole-4-carboxamide (CAS 1448038-10-5)
- 3-Cyano-N-(pyridin-4-ylmethyl)benzamide (CAS 879183-98-9)
- Ethyl Vanillate (CAS 617-05-0)
- N-[(6-pyrazol-1-ylpyridin-3-yl)methyl]-4,6-dipyrrolidin-1-yl-1,3,5-triazin-2-amine (CAS 1172698-34-8)
- 4-(6-Aminopyridin-3-yl)benzaldehyde (CAS 1314988-20-9)
- 5-(2-Morpholinoethyl)-1,3,4-oxadiazole-2-thiol (CAS 113657-10-6)
- 2,2,3,3,4,4-Hexafluoropentanediamide (CAS 507-68-6)
- 2-(6-methyl-1H-1,3-benzodiazol-1-yl)acetic acid hydrochloride (CAS 1795495-25-8)
- Thymopoietin II Peptide Fragment (CAS 56795-64-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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