4-(3,4-Dichlorophenyl)tetrahydro-2H-pyran-4-carbonitrile CAS 1035262-24-8
| CAS No. | 1035262-24-8 |
| Molecular Formula | C12H11Cl2NO |
| Molecular Weight | 256.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-(3,4-Dichlorophenyl)tetrahydro-2H-pyran-4-carbonitrile (CAS 1035262-24-8) is a high-purity analytical reference standard with the molecular formula C12H11Cl2NO and a molecular weight of 256.13 g/mol.
The molecular framework of 4-(3,4-Dichlorophenyl)tetrahydro-2H-pyran-4-carbonitrile (C12H11Cl2NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 4-(3,4-Dichlorophenyl)tetrahydro-2H-pyran-4-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H11Cl2NO |
| Molecular Weight | 256.13 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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- 2-(5-(3,4-Dichlorophenyl)-1H-pyrazol-1-yl)ethanamine (CAS 1707375-41-4)
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Recommended Standards
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- N-(5-bromopyridin-2-yl)thiazol-2-amine (CAS 350511-12-5)
- 2-(Pyridin-4-yl)-6-(trifluoromethyl)-1H-benzo[d]imidazole (CAS 91437-89-7)
- (R)-1-benzylpyrrolidine-2-carbonitrile (CAS 1260602-71-8)
- 1420880-42-7 4'-Bromomethyl-2-cyanobiphenyl-d4 (CAS 1420880-42-7)
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- Benzyl 2-((5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl)thio)acetate (CAS 896376-66-2)
- (4-Fluorophenyl)(1-methyl-1H-imidazol-2-yl)methanol (CAS 122155-26-4)
- 4-(Chloromethyl)-1-ethoxy-4-methylhexane (CAS 1463472-56-1)
- (2-((Trifluoromethyl)thio)phenyl)boronic acid (CAS 947533-17-7)
- Allyl (3,4-dichlorophenyl)carbamate (CAS 25217-32-7)
- Insulin Degludec Impurity 26 (CAS CATO-C4X-215726)
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