2-chloro-1-{1H-pyrrolo[2,3-b]pyridin-3-yl}propan-1-one CAS 1037152-84-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1037152-84-3
Molecular FormulaC10H9ClN2O
Molecular Weight208.64 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-chloro-1-{1H-pyrrolo[2,3-b]pyridin-3-yl}propan-1-one CAS 1037152-84-3 chemical structure

Description

As a certified reference material (CRM), 2-chloro-1-{1H-pyrrolo[2,3-b]pyridin-3-yl}propan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

2-chloro-1-{1H-pyrrolo[2,3-b]pyridin-3-yl}propan-1-one (CAS 1037152-84-3) is a high-purity analytical reference standard with the molecular formula C10H9ClN2O and a molecular weight of 208.64 g/mol.

The molecular framework of 2-chloro-1-{1H-pyrrolo[2,3-b]pyridin-3-yl}propan-1-one (C10H9ClN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC10H9ClN2O
Molecular Weight208.64 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1988
Halogen ContentCl-containing
Nitrogen Atoms2

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