(R)-2-hydroxypropyl 4-methylbenzenesulfonate CAS 103775-61-7
| CAS No. | 103775-61-7 |
| Molecular Formula | C10H14O4S |
| Molecular Weight | 230.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (R)-2-hydroxypropyl 4-methylbenzenesulfonate.
(R)-2-hydroxypropyl 4-methylbenzenesulfonate (CAS 103775-61-7) is a high-purity analytical reference standard with the molecular formula C10H14O4S and a molecular weight of 230.28 g/mol.
The molecular framework of (R)-2-hydroxypropyl 4-methylbenzenesulfonate (C10H14O4S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H14O4S |
| Molecular Weight | 230.28 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Sulfur Atoms | 1 |
Related R Standards
- (S)-2-Hydroxypropyl 4-methylbenzenesulfonate (CAS 32464-98-5)
- 3-Hydroxypropyl 4-methylbenzenesulfonate (CAS 81842-71-9)
- 2-(2-Hydroxypropyl)-6-phenylpyridazin-3(2H)-one (CAS 59594-39-7)
- 2-Hydroxypropyl decanoate (CAS 88357-29-3)
- 1-(3-Hydroxypropyl)-5-(3-methylthiophen-2-yl)pyrimidine-2,4(1H,3H)-dione (CAS 952402-29-8)
- N-(3-Hydroxypropyl)-4-methylbenzenesulfonamide (CAS 13379-98-1)
- N-(2-hydroxypropyl)-4-methylbenzenesulfonamide (CAS 59724-53-7)
- Methyl 2-((1-(3-hydroxypropyl)piperidin-4-yl)oxy)acetate (CAS 2725904-34-5)
Recommended Standards
- Tert-butyl ((1R,5S)-5-fluoro-3-azabicyclo[3.2.0]Heptan-1-yl)carbamate (CAS 1037367-02-4)
- 4-(Aminomethyl)-2-fluoro-N-methyl-N-phenylaniline (CAS 1039891-13-8)
- N1-benzyl-4-fluoro-N1-methylbenzene-1,2-diamine (CAS 1019582-09-2)
- 5-Amino-n-ethyl-2-methoxybenzenesulfonamide (CAS 1041574-52-0)
- n-(3,3,3-Trifluoropropyl)cyclopentanamine (CAS 1183610-06-1)
- 3-(Naphthalen-2-yl)benzaldehyde (CAS 728919-26-4)
- 2-{8-oxa-3-azabicyclo[3.2.1]octan-3-yl}ethan-1-aminehydrochloride (CAS 1955548-18-1)
- Dichlormid (CAS 37764-25-3)
- rac-3-Octadecanamido-2-Ethoxypropan-1-ol Phosphocholine (CAS 112989-02-3)
- rac-[(2R,3R)-2-(3-cyclopropyl-1,2,4-oxadiazol-5-yl)oxolan-3-yl]methanamine hydrochloride (CAS 2031242-44-9)
- Ixazomib Impurity 47 (CAS CATO-C4X-126747)
- N-(((Benzyloxy)carbonyl)oxy)-2-(quinolin-8-yloxy)acetimidamide (CAS 88758-51-4)
- 3-(4-(5-Chloro-2-methylphenyl)piperazin-1-yl)propan-1-amine (CAS 899425-88-8)
- Semaglutide impurity 64 (CAS CATO-C4X-222664)
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