3-(4-(TRIFLUOROMETHYL)PHENYL)-1H-PYRAZOLE-5-CARBOXYLIC ACID CAS 1038398-68-3
| CAS No. | 1038398-68-3 |
| Molecular Formula | C11H7F3N2O2 |
| Molecular Weight | 256.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 256.18 g/mol gives 3-(4-(TRIFLUOROMETHYL)PHENYL)-1H-PYRAZOLE-5-CARBOXYLIC ACID distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-(4-(TRIFLUOROMETHYL)PHENYL)-1H-PYRAZOLE-5-CARBOXYLIC ACID (CAS 1038398-68-3) is a high-purity analytical reference standard with the molecular formula C11H7F3N2O2 and a molecular weight of 256.18 g/mol.
The molecular framework of 3-(4-(TRIFLUOROMETHYL)PHENYL)-1H-PYRAZOLE-5-CARBOXYLIC ACID (C11H7F3N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(4-(TRIFLUOROMETHYL)PHENYL)-1H-PYRAZOLE-5-CARBOXYLIC ACID meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H7F3N2O2 |
| Molecular Weight | 256.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related TRIFLUOROMETHYL Standards
- 3-[4-[3-(Trifluoromethyl)-3H-diazirin-3-yl]phenyl]-2E-propenoic acid (CAS 1002328-38-2)
- 3-(3-(Trifluoromethyl)-1H-pyrazol-5-yl)benzoic acid (CAS 1031417-48-7)
- 3-[2-(trifluoromethyl)phenyl]-1H-pyrazole-5-carboxylic acid (CAS 1038770-76-1)
- N-(5-(Trifluoromethyl)isoxazol-3-yl)benzamide (CAS 110235-11-5)
- 1-(4-(Trifluoromethyl)phenyl)-1H-pyrazole-3-carboxylic acid (CAS 1143521-43-0)
- 3-[5-(trifluoromethyl)-1h-pyrazol-1-yl]benzoic acid (CAS 1152530-82-9)
- 5-[2-(Trifluoromethyl)phenyl]-1h-pyrazole-4-carboxylic acid (CAS 1152539-99-5)
- 5-[3-(Trifluoromethyl)phenyl]-1h-pyrazole-4-carboxylic acid (CAS 1152543-70-8)
Recommended Standards
- 6-Amino-2-(trifluoromethyl)quinoline-4-carboxylic acid (CAS 1023814-31-4)
- n-(2-Bromobenzyl)-3-methylbutan-2-amine (CAS 1040309-12-3)
- [1-(2-Bromophenyl)ethyl](2-methylpropyl)amine (CAS 1019628-97-7)
- 4-Amino-8-(trifluoromethyl)quinoline-3-carboxylic acid (CAS 1049127-39-0)
- 3-(2-Methyl-1h-1,3-benzodiazol-1-yl)propanoic acid hydrochloride (CAS 58555-22-9)
- (R)-4-ethyl-4-hydroxy-1,7-dihydro-3H-pyrano[3,4-c]pyridine-3,8(4H)-dione (CAS 2090799-24-7)
- 2-(tert-Butyl)-3-fluorophenol (CAS 1206776-18-2)
- 2-Amino-5-(ethoxymethyl)-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one (CAS 2060062-51-1)
- 2,7-Dibromo-9,9,10,10-tetrafluoro-9,10-dihydrophenanthrene (CAS 187023-89-8)
- N-Methyl-N-[3-(trifluoromethyl)phenyl]thiocarbamoyl chloride (CAS 83508-62-7)
- 731772-01-3 1-(2-Bromoprop-2-en-1-yl)-2-chlorobenzene DTXSID30641107 (CAS 731772-01-3)
- 3-[1-(2-Chlorobenzyl)-2,5-dioxoimidazolidin-4-yl]propanoic acid (CAS 1955494-59-3)
- (R)-1-Cyclohexyl-2,2,2-trifluoroethanamine hydrochloride (CAS 2564735-97-1)
- Semaglutide impurity 25 (CAS CATO-C4X-222625)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com