LCZ-696 Impurity 2 HCl CAS 1038924-71-8
| CAS No. | 1038924-71-8 |
| Molecular Formula | C18H21NO2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
LCZ-696 Impurity 2 HCl (CAS 1038924-71-8) is a certified pharmaceutical impurity reference standard with the molecular formula C18H21NO2HCl and a molecular weight of 319.83 g/mol.
Based on its molecular formula C18H21NO2HCl, LCZ-696 Impurity 2 HCl contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 319.83 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures LCZ-696 Impurity 2 HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H21NO2 HCl |
| Molecular Weight | 319.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- Rosuvastatin Impurity 139 (CAS CATO-C4X-1169139)
- Difluprednate Impurity 5 (CAS 1270039-29-6)
- Indacaterol Impurity 57 HCl (CAS 312753-56-3(Free base))
- 3-ethylpentan-3-amine hydrochloride (CAS 56065-46-4)
- 6-Vinylquinoxaline (CAS 874279-33-1)
- diethyl 2-[5-(trifluoromethyl)pyridin-2-yl]malonate (CAS 153704-26-8)
- 2,2,2-Trifluoro-1-(3-hydroxyphenyl)ethanone (CAS 326897-98-7)
- 1,7-Heptanediol-2,4,6-<SUP>13</SUP>C<SUB>3</SUB> (CAS 1173023-54-5)
- 2-Fluoro-5-methyl-N-phenylaniline (CAS 155310-23-9)
- D-Glu3-Tirzepatide (CAS CATO-CPTD788927)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com