5-Chloro-1-methyl-1H-benzimidazole CAS 10394-36-2
| CAS No. | 10394-36-2 |
| Molecular Formula | C8H7ClN2 |
| Molecular Weight | 166.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5-Chloro-1-methyl-1H-benzimidazole (CAS 10394-36-2) is a high-purity analytical reference standard with the molecular formula C8H7ClN2 and a molecular weight of 166.61 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, 5-Chloro-1-methyl-1H-benzimidazole is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 166.61 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 5-Chloro-1-methyl-1H-benzimidazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H7ClN2 |
| Molecular Weight | 166.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 5-Chloro-6-methyl-1H-pyrrolo[2,3-b]pyridine (CAS 1000340-18-0)
- 6-Chloro-5-methyl-1H-indazole (CAS 1000341-02-5)
- 3-Chloro-7-methyl-1H-pyrrolo[3,2-c]pyridine (CAS 1000341-46-7)
- 5-Chloro-6-methyl-2H-indazole (CAS 1000343-64-5)
- 2-(2-Chloro-6-methylpyridin-3-yl)acetonitrile (CAS 1000514-91-9)
- 2-(6-Chloro-2-methylpyridin-3-yl)acetonitrile (CAS 1000529-85-0)
- 6-Chloro-2,4-dimethylpyridine-3-carbonitrile (CAS 101251-72-3)
- 2-Chloro-6-Methylimidazo[1,2-a]pyridine (CAS 1019019-96-5)
Recommended Standards
- 1-Chloro-3-methylpyrrolo[1,2-a]pyrazine (CAS 1025054-90-3)
- 6-Chloro-1-methyl-1h-benzo[d]imidazole (CAS 10406-94-7)
- 5-Chloro-4-methyl-7-azaindole (CAS 1020056-87-4)
- 6-Chloro-7-methyl-1H-pyrrolo[3,2-c]pyridine (CAS 1082040-88-7)
- 4-(4-Benzylpiperazin-1-yl)benzoic acid (CAS 94038-26-3)
- 3-(Aminomethyl)quinuclidin-3-ol (CAS 128200-13-5)
- 5-(4-Chlorophenyl)cyclohexane-1,3-dione (CAS 27463-38-3)
- 1-Acetyl-3-(BOC-Amino)pyrrolidine (CAS 881298-14-2)
- (2,2′-Bipyridine-κN1,κN1′)bis[3,5-difluoro-2-(5-methyl-2-pyridinyl-κN)phenyl-κC]-, (OC-6-33)-Iridium(1+), hexafluorophosphate(1-) (1:1) (CAS 1335047-29-4)
- 3-(3,4-dichlorophenyl)aniline (CAS 926201-88-9)
- 6-Ethyl-5-propylthiomorpholine-3-carboxylic acid (CAS 1561987-99-2)
- Benzenesulfinic acid, 3-bromo-, sodium salt (1:1) (CAS 89520-70-7)
- (R)-Methyl 2-((tert-butoxycarbonyl)amino)-3-chloropropanoate (CAS 651035-84-6)
- Liraglutide Impurity 16 TFA Salt (CAS CATO-C4X-199216)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com