1,3-Dimethyl-8-(thiophene-2-carbonyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione CAS 1040648-30-3
| CAS No. | 1040648-30-3 |
| Molecular Formula | C14H17N3O3S |
| Molecular Weight | 307.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1,3-Dimethyl-8-(thiophene-2-carbonyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1,3-Dimethyl-8-(thiophene-2-carbonyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione (CAS 1040648-30-3) is a high-purity analytical reference standard with the molecular formula C14H17N3O3S and a molecular weight of 307.37 g/mol.
The molecular framework of 1,3-Dimethyl-8-(thiophene-2-carbonyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione (C14H17N3O3S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1,3-Dimethyl-8-(thiophene-2-carbonyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H17N3O3S |
| Molecular Weight | 307.37 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- 4-(Benzo[d]thiazol-2-yl)-1-(m-tolyl)-1H-1,2,3-triazol-5-amine (CAS 1032227-71-6)
- Trans-4-oxo-1,6-diphenyl-2-thioxohexahydropyrimidine-5-carbonitrile (CAS 110214-43-2)
- (E)-1-Bromo-4-methylpent-2-ene (CAS 66222-05-7)
- 4-Amino-5-iodo-2-methoxybenzonitrile (CAS 380241-63-4)
- N-ethyl-N-hydroxyacetamide (CAS 63087-07-0)
- 1-[(4-Fluorobenzyl)oxy]-3-(4-methylbenzyl)-1H-imidazole-2,4,5(3H)-trione (CAS 320422-96-6)
- Methyl 2-(4-formylphenoxy)propanoate (CAS 70129-95-2)
- 4-Benzyl-5-(piperidin-1-ylmethyl)-4h-1,2,4-triazole-3-thiol (CAS 790263-73-9)
- N-[(1,1-dimethylethoxy)carbonyl]-N-methyl-O-(phenylmethyl)-L-Threonine (CAS 250375-08-7)
- N-(furan-2-ylmethyl)-2,3-dimethylcyclohexan-1-amine (CAS 1132675-33-2)
- (R)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-2-(3-methoxybenzyl)propanoic acid (CAS 1260601-49-7)
- Liraglutide Impurity 26 (CAS CATO-C4X-199226)
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