((3-Chloro-4-fluorophenyl)sulfonyl)-L-leucine CAS 1041437-99-3
| CAS No. | 1041437-99-3 |
| Molecular Formula | C12H15ClFNO4S |
| Molecular Weight | 323.77 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, ((3-Chloro-4-fluorophenyl)sulfonyl)-L-leucine (C12H15ClFNO4S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 323.77 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
((3-Chloro-4-fluorophenyl)sulfonyl)-L-leucine (CAS 1041437-99-3) is a high-purity analytical reference standard with the molecular formula C12H15ClFNO4S and a molecular weight of 323.77 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), ((3-Chloro-4-fluorophenyl)sulfonyl)-L-leucine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H15ClFNO4S |
| Molecular Weight | 323.77 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 4-(3-Chlorobenzoyl)-1-oxa-4-azaspiro[4.5]decane-3-carboxylic acid (CAS 1008471-35-9)
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- N-Chloroacetyl-DL-phenylalanine (CAS 7765-11-9)
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- 20,22-Dihydro-digitoxigenin (CAS 4427-85-4)
- 1-(2-Amino-3,6-dibromophenyl)naphthalen-2-ol (CAS 1424386-43-5)
- N,4-Dimethyl-1H-imidazole-5-carboxamide (CAS 137480-35-4)
- 2-Methoxy-4-methyl-5-(piperidin-2-yl)pyridine (CAS 1270425-33-6)
- (4aR,8aR)-rel-1-methyl-decahydro-1,5-naphthyridine oxalic acid (CAS 2007919-59-5)
- Vulgaxanthin-I (CAS 904-62-1)
- Potassium 2-methoxy-4-nitrophenolate (CAS 304675-72-7)
- Semaglutide impurity 55 (CAS CATO-C4X-222655)
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