3-Chloro-N-cyclohexyl-5-(trifluoromethyl)pyridin-2-amine CAS 1041565-07-4
| CAS No. | 1041565-07-4 |
| Molecular Formula | C12H14ClF3N2 |
| Molecular Weight | 278.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Chloro-N-cyclohexyl-5-(trifluoromethyl)pyridin-2-amine (CAS 1041565-07-4), molecular formula C12H14ClF3N2 and molecular weight 278.70 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution, 3-Chloro-N-cyclohexyl-5-(trifluoromethyl)pyridin-2-amine is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 278.70 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H14ClF3N2 |
| Molecular Weight | 278.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]azepane (CAS 1219967-95-9)
- 3-Chloro-2-(4-methyl-1-piperidinyl)-5-(trifluoromethyl)pyridine (CAS 1219980-96-7)
- 3-Chloro-2-(2-methyl-1-piperidinyl)-5-(trifluoromethyl)pyridine (CAS 1220029-27-5)
- 3-Chloro-2-(3-methyl-1-piperidinyl)-5-(trifluoromethyl)pyridine (CAS 1220036-31-6)
- 6-Chloro-1-oxo-1-(3-trifluoromethylphenyl)hexane (CAS 898783-58-9)
- 6-Chloro-1-oxo-1-(4-trifluoromethylphenyl)hexane (CAS 890043-20-6)
- ethyl 7-chloro-6-fluoro-4-oxo-chromene-2-carboxylate (CAS 2530127-56-9)
- N-(4-chloro-3-(trifluoromethyl)phenyl)piperidin-4-amine (CAS 886506-66-7)
Recommended Standards
- Clofencet (CAS 129025-54-3)
- 2-Amino-4-chloro-7-((1-methyl-1H-pyrazol-3-yl)methyl)-5H-pyrrolo[2,3-d]pyrimidin-6(7H)-one (CAS 1196886-83-5)
- Ensifentrine impurity 46 (CAS CATO-C4X-335346)
- Ensifentrine impurity 44 (CAS CATO-C4X-335344)
- Magnesiummethacrylate (CAS 7095-16-1)
- 2-((Carboxymethyl)(methyl)amino)-2-oxoacetic acid (CAS 82505-42-8)
- 3-(Chlorosulfonyl)-5-fluorobenzoic acid (CAS 912577-43-6)
- N,N-Dibutyl-5,8-dimethoxy-2-methylquinolin-4-amine (CAS 66890-19-5)
- (3-Isopropyltetrahydrofuran-2-yl)methanamine hydrochloride (CAS 1955541-51-1)
- 6-Methyl-5-(o-tolyl)thiazolo[3,2-b][1,2,4]triazole (CAS 1574587-70-4)
- 2,3-Difluoro-1-methyl-4-nitrobenzene (CAS 932373-72-3)
- 2-Fluoro-4-(trifluoromethyl)cinnamic acid (CAS 262608-88-8)
- 2-(5-Methylfuran-2-yl)quinoline-4-carbohydrazide (CAS 524733-46-8)
- Anti-TF Antigen Peptide P30-1 trifluoroacetate salt (CAS 573664-50-3)
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