Estriol impurity 24 CAS 104202-84-8
| CAS No. | 104202-84-8 |
| Molecular Formula | C24H38O3Si |
| Molecular Weight | 402.64 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Estriol impurity 24 is closely related to a steroid core, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Estriol impurity 24 (CAS 104202-84-8, C24H38O3Si) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C24H38O3Si, Estriol impurity 24 contains a steroid core, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 402.64 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H38O3Si |
| Molecular Weight | 402.64 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
Related Estriol Standards
- Estriol Impurity N2 (CAS 177714-21-5)
- Estriol Impurity 26 (CAS CATO-C4X-163726)
- Estriol Triacetate (CAS 2284-32-4)
- Estriol 3-Succinate (CAS 47575-61-1)
- Estriol Succinate (CAS 514-68-1)
- Estriol Impurity 15 (CAS CATO-C4X-163715)
- Estriol Impurity 13 (CAS CATO-C4X-163713)
- Estriol 3-Benzyl Ether (CAS 18650-87-8)
Recommended Standards
- 3-Methyl-2-(pentadecylthio)quinazolin-4(3H)-one (CAS 89861-50-7)
- Cholesterol-5α,6α-epoxide (CAS 1250-95-9)
- 3-Bromo-4-((2-chloro-4-fluorobenzyl)oxy)-5-ethoxybenzamide (CAS 1706447-70-2)
- 26- Hydroxycholesterol (CAS 13095-61-9)
- Nintedanib Impurity 107 (CAS CATO-C4X-1814107)
- Linagliptin Impurity N31 (CAS 586408-08-4)
- Cefixime Impurity 10 (CAS CATO-C4X-113910)
- (R)-2-(6-Aminobenzo[d]thiazol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid (CAS 5571-98-2)
- (Z)-N'-[(2,4-Dichlorophenyl)methoxy]pyridine-4-carboximidamide (CAS 338403-95-5)
- 1-(Piperidin-3-ylmethyl)piperidine (CAS 81310-56-7)
- 114604-96-5 1H-Indole-1-carboxylic acid, 2-formyl-, 1,1-dimethylethyl ester ACMC-20mkkr (CAS 114604-96-5)
- 4-Aminobicyclo[2.1.1]Hexane-1-carbonitrile hydrochloride (CAS 2170371-94-3)
- 1,5-Dibenzyl Glutarate 56977-08-3 Dibenzyl Pentanedioate Glutaric Acid Dibenzyl Ester Pentanedioic Acid 1,5-Bis(phenylmethyl) Ester (CAS 56977-08-3)
- Semaglutide impurity 37 (CAS CATO-C4X-222637)
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