Quinolin-2-ylmethanesulfonyl chloride CAS 1042787-06-3
| CAS No. | 1042787-06-3 |
| Molecular Formula | C10H8ClNO2S |
| Molecular Weight | 241.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies Quinolin-2-ylmethanesulfonyl chloride (CAS 1042787-06-3), a certified reference material (molecular formula C10H8ClNO2S, MW 241.69 g/mol) for analytical method development and quality control.
Quinolin-2-ylmethanesulfonyl chloride (C10H8ClNO2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H8ClNO2S |
| Molecular Weight | 241.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Quinolin Standards
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- 4-Methyl-5-(quinolin-6-yl)-4H-1,2,4-triazole-3-thiol (CAS 306935-38-6)
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Recommended Standards
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- 1-(6-chloropyridin-2-yl)-5-cyclopropylpyrazole-4-carboxylic acid (CAS 1820711-13-4)
- (2E)-3-(4-Ethoxyphenyl)-1-(2-methoxyphenyl)prop-2-en-1-one (CAS 1181788-49-7)
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