rel-(1R,2R,3S,4S)-3-Aminobicyclo[2.2.1]heptane-2-carboxylic acid CAS 104308-53-4
| CAS No. | 104308-53-4 |
| Molecular Formula | C8H13NO2 |
| Molecular Weight | 155.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
rel-(1R,2R,3S,4S)-3-Aminobicyclo[2.2.1]heptane-2-carboxylic acid (CAS 104308-53-4), molecular formula C8H13NO2 and molecular weight 155.19 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of rel-(1R,2R,3S,4S)-3-Aminobicyclo[2.2.1]heptane-2-carboxylic acid (C8H13NO2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), rel-(1R,2R,3S,4S)-3-Aminobicyclo[2.2.1]heptane-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H13NO2 |
| Molecular Weight | 155.19 g/mol |
| Appearance | White to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1986 |
| Nitrogen Atoms | 1 |
Recommended Standards
- Methyl 1-cyclopropylazetidine-2-carboxylate (CAS 1042413-86-4)
- ethyl 4-cyano-2-methylbutanoate (CAS 10444-16-3)
- (R)-3,3-Dimethyltetrahydropyrrolo[1,2-c]oxazol-5(3H)-one (CAS 103630-36-0)
- (2R,3aR,6aR)-octahydrocyclopenta[b]pyrrole-2-carboxylic acid (R)-Endo-cis-2-azabicyclo[3,3,0]octane-3-carboxylic acid 105307-53-7 (CAS 105307-53-7)
- 4-{[(5-amino-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}benzonitrile (CAS 299921-59-8)
- N-(4-(3-((4-Chlorophenyl)sulfonyl)azetidine-1-carbonyl)phenyl)acetamide (CAS 1448136-62-6)
- 3-(2-Fluorophenoxy)-7-hydroxy-2-methyl-4h-chromen-4-one (CAS 315234-43-6)
- α-Acetyl-ω-hydroxy-Poly(oxy-1,2-ethanediyl) (CAS 27613-77-0)
- 2-(Benzylthio)-4,6-dimethylpyrimidine (CAS 3613-70-5)
- (2S,3S)-1-Benzyl-3-Hydroxypyrrolidine-2-Carboxylic Acid Hydrochloride (CAS 1422284-79-4)
- N-[2-(p-Bromocinnamylamino)ethyl]-5-Isoquinoline Sulfonamide (CAS 127243-85-0)
- 6-fluoronaphthalen-1-amine (CAS 62078-78-8)
- 4-Amino-2-(oxazolo[4,5-b]pyridin-2-yl)phenol (CAS 443636-20-2)
- C-Type Natriuretic Peptide (32-53) (human, porcine, rat) (CAS 127869-51-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com