6-Fluoro-1H-indole-3-carbonitrile CAS 1043601-53-1
| CAS No. | 1043601-53-1 |
| Molecular Formula | C9H5FN2 |
| Molecular Weight | 160.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 6-Fluoro-1H-indole-3-carbonitrile (CAS 1043601-53-1), a certified reference material (molecular formula C9H5FN2, MW 160.15 g/mol) for analytical method development and quality control.
6-Fluoro-1H-indole-3-carbonitrile (C9H5FN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H5FN2 |
| Molecular Weight | 160.15 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
- 7-Fluoro-1H-indole-3-carbonitrile (CAS 1043601-55-3)
- 6-Fluoro-1H-indole-4-carbonitrile (CAS 1082040-44-5)
- 7-Fluoro-1H-indole-4-carbonitrile (CAS 1154742-54-7)
- 5-Fluoro-1H-indole-6-carbonitrile (CAS 1201149-04-3)
- 4-Fluoro-1H-indole-3-carbonitrile (CAS 1260759-82-7)
- 4-Fluoro-1H-indole-6-carbonitrile (CAS 1427389-62-5)
- 7-fluoro-1H-indole-2-carbonitrile (CAS 1539961-71-1)
- 5-Fluoro-1H-indole-3-carbonitrile (CAS 194490-15-8)
Recommended Standards
- 2-(Cyanomethyl)-4-fluorobenzonitrile (CAS 1000540-75-9)
- 4-(Cyanomethyl)-3-fluorobenzonitrile (CAS 1000516-58-4)
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- 372942-43-3 Acetic-d3 acid, 2,5-dioxopyrrolidin-1-yl ester N-Acetoxy-d3-succinimide (CAS 372942-43-3)
- PC Mal-NHS carbonate ester (CAS 1408057-91-9)
- 4,5,6,7-tetrahydro-2H-isoindol-5-amine (CAS 73983-58-1)
- 2,5-Dimethoxyphenylisothiocyanate (CAS 40532-06-7)
- 2-Bromo-N,4-dimethyl-6-nitroaniline (CAS 1805598-11-1)
- 1-{2-[3-Methyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]ethyl}pyrrolidine (CAS 2096995-82-1)
- 2-Amino-4-(ethylthio)-2-methylbutan-1-ol (CAS 1343746-93-9)
- N-(4-Fluorophenyl)-2-(8-methyl-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetamide (CAS 853323-51-0)
- 1-Acetylindoline-5-carbonitrile (CAS 15861-29-7)
- 3-((Methylthio)methyl)piperidine hydrochloride (CAS 1211487-14-7)
- Des-His(1)-Semaglutide (CAS CATO-C4X-2226216)
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