2-(6,7-Dimethoxy-2-(phenylsulfonyl)-1,2,3,4-tetrahydroisoquinolin-1-yl)acetic acid CAS 10447-22-0
| CAS No. | 10447-22-0 |
| Molecular Formula | C19H21NO6S |
| Molecular Weight | 391.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(6,7-Dimethoxy-2-(phenylsulfonyl)-1,2,3,4-tetrahydroisoquinolin-1-yl)acetic acid is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-(6,7-Dimethoxy-2-(phenylsulfonyl)-1,2,3,4-tetrahydroisoquinolin-1-yl)acetic acid (CAS 10447-22-0), molecular formula C19H21NO6S and molecular weight 391.44 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, 2-(6,7-Dimethoxy-2-(phenylsulfonyl)-1,2,3,4-tetrahydroisoquinolin-1-yl)acetic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 391.44 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(6,7-Dimethoxy-2-(phenylsulfonyl)-1,2,3,4-tetrahydroisoquinolin-1-yl)acetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H21NO6S |
| Molecular Weight | 391.44 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Dimethoxy Standards
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- 2,2'-(2,5-Dimethoxy-1,4-phenylene)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane) (CAS 1338777-82-4)
- 7,8-Dimethoxy-2-(quinolin-2-yl)-4H-chromen-4-one (CAS 6622-20-4)
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Recommended Standards
- 1-(2-(4-Ethylphenoxy)acetyl)-4-((4-methylphenyl)sulfonyl)semicarbazide (CAS 1024439-41-5)
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- Fmoc-His-OMe (CAS 160450-10-2)
- 2-(2-(Diphenylphosphino)phenyl)-1-methyl-1H-indole (CAS 1067883-56-0)
- Cyclobutyl 2-thiomethylphenyl ketone (CAS 898790-56-2)
- 2-(2-((1,1,1-Trifluoropropan-2-yl)oxy)ethoxy)ethane-1-sulfonyl chloride (CAS 1539802-98-6)
- 1616506-48-9 KS-000024XO methyl (2S)-2-acetamido-3-[4-(morpholin-4-yl)phenyl]propanoate >98%ee (CAS 1616506-48-9)
- (R)-tert-Butyl 3-ethylpiperazine-1-carboxylate hydrochloride (CAS 1217462-84-4)
- (3R,4r,5S)-Piperidine-3,4,5-triol (CAS 13042-55-2)
- 1-Bromo-4-ethoxy-2-fluorobenzene (CAS 107713-66-6)
- 2-(Benzyloxy)-5-(3-quinolinyl)benzaldehyde (CAS 893741-20-3)
- 7-Bromo-4,4-difluoro-3,4-dihydroisoquinolin-1(2H)-one (CAS 2239309-55-6)
- Ethyl 4-((2,5-dimethylphenyl)thio)butanoate (CAS 1707580-40-2)
- Prolactin-Releasing Peptide (12-31), rat (CAS 222988-10-5)
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