17-Hydroxy-5β-pregnane-3,11,20-trione CAS 10455-93-3
| CAS No. | 10455-93-3 |
| Molecular Formula | C21H30O4 |
| Molecular Weight | 346.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 17-Hydroxy-5β-pregnane-3,11,20-trione is closely related to a flavonoid core, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 17-Hydroxy-5β-pregnane-3,11,20-trione (CAS 10455-93-3), a certified reference material (molecular formula C21H30O4, MW 346.46 g/mol) for analytical method development and quality control.
17-Hydroxy-5β-pregnane-3,11,20-trione (C21H30O4) contains a flavonoid core, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H30O4 |
| Molecular Weight | 346.46 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
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Recommended Standards
- 5β-Pregnan-21-ol-3,11,20-trione (CAS 10417-86-4)
- N-Cyclohexyl L-Z-isoleucinamide (CAS 1071594-16-5)
- n-{[1-(dimethylamino)cycloheptyl]methyl}-3,4-dihydro-2h-1,5-benzodioxepine-7-carboxamide (CAS 1015664-71-7)
- Cannabitriol (CAS 11003-36-4)
- N-hydroxy-1-phenylcyclobutane-1-carboximidamide (CAS 1053657-11-6)
- 2,4,6-Tri-thiophen-2-yl-[1,3,5]triazine (CAS 56382-53-7)
- 1-(4-((Methylamino)methyl)piperidin-1-yl)ethan-1-one (CAS 1353944-09-8)
- 4-Bromo-3-hydroxyphenylboronic acid pinacol ester (CAS 2121512-98-7)
- methyl (S)-2-hydroxy-3-mercaptopropanoate (CAS 103004-09-7)
- (3-(Hydroxymethyl)piperidin-1-yl)(4-methylthiazol-5-yl)methanone (CAS 1155632-04-4)
- Methyl 2-((3-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-1,2,4-oxadiazol-5-yl)oxy)acetate (CAS 1823183-97-6)
- 4-[(Benzenesulfonyl)methyl]-6-(methylsulfanyl)-2-phenylpyrimidine (CAS 303147-44-6)
- (3-Chloro-4-((3,4-dichlorobenzyl)oxy)-5-ethoxyphenyl)methanol (CAS 678158-52-6)
- (D-Ala1)-Peptide T amide (CAS 106362-34-9)
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