1-(4-Cyanobenzyl)piperidine-2-carboxylic acid CAS 1045893-49-9
| CAS No. | 1045893-49-9 |
| Molecular Formula | C14H16N2O2 |
| Molecular Weight | 244.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 1-(4-Cyanobenzyl)piperidine-2-carboxylic acid (CAS 1045893-49-9), a certified reference material (molecular formula C14H16N2O2, MW 244.29 g/mol) for analytical method development and quality control.
1-(4-Cyanobenzyl)piperidine-2-carboxylic acid (C14H16N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H16N2O2 |
| Molecular Weight | 244.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Nitrogen Atoms | 2 |
Related Cyanobenzyl Standards
- 1-(2-Cyanobenzyl)piperidine-4-carboxylic acid (CAS 1153070-82-6)
- 1-(2-Cyanobenzyl)piperidine-2-carboxylic acid (CAS 1218096-48-0)
- n-(3-Cyanobenzyl)tetrahydro-2h-pyran-4-carboxamide (CAS 1271663-97-8)
- n-(4-Cyanobenzyl)tetrahydro-2h-pyran-4-carboxamide (CAS 1275546-90-1)
- 1-(4-Cyanobenzyl)piperidine-4-carboxylic acid (CAS 939757-55-8)
- 2-(4-Cyanobenzyl)thiazole-4-carboxylic acid (CAS 2253525-96-9)
- 1-(4-Cyanobenzyl)piperidine-4-carboxamide (CAS 945298-47-5)
- 2-((4-Cyanobenzyl)(methyl)amino)-N-propylacetamide (CAS 1240816-23-2)
Recommended Standards
- 3-(4-Isopropylphenyl)-1H-pyrazole-5-carbohydrazide (CAS 1044837-29-7)
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- Ethyl 4-(dimethylamino)quinoline-3-carboxylate (CAS 1049114-68-2)
- 2-(1-Methyl-5-(2,2,2-trichloroacetyl)-1H-pyrrol-2-yl)acetonitrile (CAS 299918-21-1)
- 1-Boc-4-Bromoindole (CAS 676448-17-2)
- Methyl (R)-2-(1-((tert-butoxycarbonyl)amino)ethyl)-5-methyloxazole-4-carboxylate (CAS 343339-23-1)
- 3-(Cyclohexylmethyl)-5-((2,5-dichlorobenzyl)thio)-8,9-dimethoxyimidazo[1,2-c]quinazolin-2(3H)-one (CAS 920529-91-5)
- 3,4,5-Tribromo-2,6-dimethylpyridine (CAS 1379303-06-6)
- 5-Bromo-2,3-dioxoindoline-7-carboxylic acid (CAS 1452166-15-2)
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- Gadolinium(III) bromide (CAS 13818-75-2)
- Semaglutide impurity 237 (CAS CATO-C4X-2226237)
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