Pramipexole EP Impurity D diHCl CAS 104632-27-1
| CAS No. | 104632-27-1 |
| Molecular Formula | C10H17N3S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Pramipexole EP Impurity D diHCl.
As a process- or degradation-related impurity, Pramipexole EP Impurity D diHCl (CAS 104632-27-1, C10H17N3SHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrile group, sulfur-containing functionality, chlorine substitution, Pramipexole EP Impurity D diHCl is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 247.78 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H17N3S 2*HCl |
| Molecular Weight | 247.78 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Pramipexole Standards
- Pramipexole Impurity 44 (CAS 1001648-65-2)
- Pramipexole USP Related Compound G (CAS 1001648-71-0)
- Pramipexole Impurity 66 (CAS 1001648-73-2)
- Pramipexole Impurity 34 (CAS 1001648-74-3)
- Pramipexole Impurity 43 (CAS 1001648-75-4)
- Pramipexole Impurity 46 (CAS 104617-49-4)
- Pramipexole Impurity 41 (CAS 104617-50-7)
- Pramipexole Impurity 17 (CAS 104617-51-8)
Recommended Standards
- Homatropine Methylbromide EP Impurity E Bromide (Atropine Methylbromide) (CAS 2870-71-5)
- Lamotrigine Dimer Impurity 8 (CAS CATO-C4X-16728)
- Ibrutinib Impurity 41 (CAS CATO-C4X-106441)
- 1-Tetrahydrofurfuryl-piperazine (CAS 82500-35-4)
- Chlorinated Naphthalene Mix 8 (CAS CATO-MCHM705004)
- (3-Methoxy-5-(trifluoromethyl)phenyl)methanol (CAS 916420-98-9)
- 4-Bromo-2,7-naphthyridin-1-amine (CAS 959558-28-2)
- 6-Chloro-3-benzofuranone (CAS 3260-78-4)
- Methyl 2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (CAS 314279-09-9)
- Tirzepatide Impurity 58 (CAS CATO-C4X-324058)
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