4-Chloro-3-nitro-1h-pyrazole-5-carbohydrazide CAS 1046463-61-9
| CAS No. | 1046463-61-9 |
| Molecular Formula | C4H4ClN5O3 |
| Molecular Weight | 205.56 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Chloro-3-nitro-1h-pyrazole-5-carbohydrazide (CAS 1046463-61-9) is a high-purity analytical reference standard with the molecular formula C4H4ClN5O3 and a molecular weight of 205.56 g/mol.
4-Chloro-3-nitro-1h-pyrazole-5-carbohydrazide (C4H4ClN5O3) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Chloro-3-nitro-1h-pyrazole-5-carbohydrazide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C4H4ClN5O3 |
| Molecular Weight | 205.56 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Chloro Standards
- 2-(3-Chloro-4-nitro-1H-pyrazol-1-yl)acetic acid (CAS 1014048-30-6)
- 3-Chloro-4-(trifluoromethyl)benzonitrile (CAS 1092460-79-1)
- Methyl 4-chloro-3-nitro-1H-pyrazole-5-carboxylate (CAS 1092782-72-3)
- 3-Chloro-2-ethynyl-5-(trifluoromethyl)pyridine (CAS 1135283-18-9)
- 2-Chloro-3-ethynyl-5-(trifluoromethyl)pyridine (CAS 1211536-59-2)
- 3-Chloro-2-(trifluoromethyl)benzonitrile (CAS 1214345-16-0)
- 2-Chloro-4-ethynyl-6-(trifluoromethyl)pyridine (CAS 1256824-61-9)
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Recommended Standards
- 4-Chloro-5,5-difluoro-5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-one (CAS 1638763-60-6)
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- 3-Chlorobenzyl Bromide (CAS 766-80-3)
- 3-Methoxy-4-nitro-1h-pyrazole-5-carbonyl chloride (CAS 1159988-54-1)
- methyl 2,3-dihydro-1-benzothiophene-3-carboxylate (CAS 39891-63-9)
- 2-(3,4-Dichlorobenzoyl)aniline (CAS 91713-52-9)
- Methyl 3-iodo-1H-pyrrolo[2,3-b]pyridine-5-carboxylate (CAS 944937-30-8)
- N-(2-bromophenyl)-2-((6-(4-chlorophenyl)-3-cyano-4-phenylpyridin-2-yl)thio)acetamide (CAS 332127-41-0)
- 2-((6-(4-Chlorophenyl)-3-cyanopyridin-2-yl)thio)acetic acid (CAS 326915-38-2)
- allyl (2S,4S)-4-(acetylthio)-2-(hydroxymethyl)pyrrolidine-1-carboxylate (CAS 136140-32-4)
- 2-[(2-Methylpropyl)sulfanyl]benzoic acid (CAS 52369-61-6)
- 2-(4-Bromophenyl)-N-(1,3-dihydroxy-2-methylpropan-2-yl)-2H-tetrazole-5-carboxamide (CAS 1396792-31-6)
- 1H-Pyrazole-3,4,5-d (CAS 51038-79-0)
- Tirzepatide-d7 Ditrifluoroacetate (CAS CATO-CPTD788698)
Why CATO?
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