N-(3-Chloro-phenyl)hydroxylamine CAS 10468-17-4
| CAS No. | 10468-17-4 |
| Molecular Formula | C6H6ClNO |
| Molecular Weight | 143.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(3-Chloro-phenyl)hydroxylamine.
N-(3-Chloro-phenyl)hydroxylamine (CAS 10468-17-4) is a high-purity analytical reference standard with the molecular formula C6H6ClNO and a molecular weight of 143.57 g/mol.
N-(3-Chloro-phenyl)hydroxylamine (C6H6ClNO) contains an amide group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(3-Chloro-phenyl)hydroxylamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H6ClNO |
| Molecular Weight | 143.57 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related N Standards
- 5-Chloro-6-methylpyridin-2-ol (CAS 103997-23-5)
- (5-Chloro pyrazin-2-yl) Methanamine (CAS 1060814-53-0)
- 4-Chloro-3-methylpyridine 1-Oxide (CAS 1073-34-3)
- 2-Chloro-3-hydrazinylpyridine (CAS 117087-45-3)
- 5-Chloro-2-methylpyridin-4(1H)-one (CAS 1196157-19-3)
- 2-Chloro-1-(1H-pyrrol-3-yl)ethanone (CAS 122450-28-6)
- 3-Chloro-2-methylpyridin-4-ol (CAS 1227499-23-1)
- 2-Chloro-5-hydroxy-4-methylpyridine (CAS 1227502-89-7)
Recommended Standards
- N-(2-Chlorophenyl)hydroxylamine (CAS 10468-16-3)
- 4-(Chloromethyl)-1,2-dihydropyridin-2-one (CAS 105590-03-2)
- 2-Chloropyridine-4-methanol (CAS 100704-10-7)
- germanium dichloride-dioxane complex (CAS 10060-11-4)
- 2-(2-Chlorophenoxy)acetonitrile (CAS 43111-31-5)
- 2-(Difluoromethyl)-4-methyl-3-nitropyridine (CAS 1805309-78-7)
- Lapirium Chloride (CAS 6272-74-8)
- 4,6-diethylpyrimidine-5-carboxylic acid (CAS 1820685-04-8)
- 1-tert-Butyl 3-ethyl (3r,4s)-4-aminopyrrolidine-1,3-dicarboxylate hydrochloride (CAS 1262849-90-0)
- tert-Butyl 4-iodo-6-phenylpyridin-3-ylcarbamate (CAS 941271-13-2)
- 2-{[(4-chlorophenyl)methyl](ethyl)amino}acetic acid hydrochloride (CAS 1311317-03-9)
- 2-(Methylsulfonylamino)benzeneboronic acid pinacol ester (CAS 380430-60-4)
- 7-Hydroxychroman-4-one, 97% (CAS 76240-27-2)
- Mast Cell Degranulating Peptide (CAS 83856-13-7)
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