1-(Cyclopentylmethyl)piperazine dihydrochloride CAS 1048649-04-2
| CAS No. | 1048649-04-2 |
| Molecular Formula | C10H20N2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(Cyclopentylmethyl)piperazine dihydrochloride (CAS 1048649-04-2) is a high-purity analytical reference standard with the molecular formula C10H20N2HCl and a molecular weight of 204.74 g/mol.
The molecular framework of 1-(Cyclopentylmethyl)piperazine dihydrochloride (C10H20N2HCl) is characterized by chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(Cyclopentylmethyl)piperazine dihydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H20N2 2*HCl |
| Molecular Weight | 204.74 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Cyclopentylmethyl Standards
- (Cyclopentylmethyl)hydrazine (CAS 1016516-96-3)
- 5-(Cyclopentylmethyl)-1,3,4-oxadiazol-2-amine (CAS 1016707-50-8)
- n-(Cyclopentylmethyl)-3,4-difluoroaniline (CAS 1021125-72-3)
- 2-(cyclopentylmethyl)oxirane (CAS 104727-79-9)
- 3-[(cyclopentylmethyl)amino]propanenitrile (CAS 1087717-80-3)
- 1-(cyclopentylmethyl)pyrrolidin-3-amine (CAS 1096341-29-5)
- (Cyclopentylmethyl)[(2,5-difluorophenyl)methyl]amine (CAS 1096788-56-5)
- N-(cyclopentylmethyl)-1H-imidazole-1-carboxamide (CAS 1096821-12-3)
Recommended Standards
- Ethyl 2,3-dibromo-6-fluorophenylacetate (CAS 1806351-09-6)
- 7-chloro-6-methoxy-1H-indazole (CAS 1019332-48-9)
- N-(Fluoromethyl)-2-hydroxy-N,N-dimethylethanaminium chloride (CAS 459424-38-5)
- 2-[(5-methyl-1h-pyrazol-1-yl)methyl]quinoline-4-carboxylic acid (CAS 956371-98-5)
- 4-(Trifluoromethyl)nicotinimidamide hydrochloride (CAS 1956385-41-3)
- Dinaphtho[2,3-d:2′,3′-f][1,3,2]dioxaphosphepin, 5,9-bis[2-(cyclohexyloxy)-1-naphthalenyl]-7-hydroxy-, 7-oxide (CAS 2168567-88-0)
- (3,5-Dichlorophenyl)(m-tolyl)methanol (CAS 844856-36-6)
- 3-Methoxy-2-butanol (CAS 53778-72-6)
- (S)-2-(3-chloro-5-(difluoromethyl)-4-fluorophenyl)pyrrolidine (CAS 1447055-22-2)
- Semaglutide impurity 108 (CAS CATO-C4X-2226108)
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