3-[(2-Aminoethyl)thio]-1-(4-fluorophenyl)-2,5-pyrrolidinedione hydrochloride CAS 1048649-31-5
| CAS No. | 1048649-31-5 |
| Molecular Formula | C12H13FN2O2S |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-[(2-Aminoethyl)thio]-1-(4-fluorophenyl)-2,5-pyrrolidinedione hydrochloride.
3-[(2-Aminoethyl)thio]-1-(4-fluorophenyl)-2,5-pyrrolidinedione hydrochloride (CAS 1048649-31-5) is a high-purity analytical reference standard with the molecular formula C12H13FN2O2SHCl and a molecular weight of 304.76 g/mol.
The molecular framework of 3-[(2-Aminoethyl)thio]-1-(4-fluorophenyl)-2,5-pyrrolidinedione hydrochloride (C12H13FN2O2SHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-[(2-Aminoethyl)thio]-1-(4-fluorophenyl)-2,5-pyrrolidinedione hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H13FN2O2S HCl |
| Molecular Weight | 304.76 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Aminoethyl Standards
- N-(2-Aminoethyl)oleamide phosphate (CAS 100021-80-5)
- Methyl 3-(2-aminoethyl)-4-methylbenzoate (CAS 1000551-41-6)
- 2-(2-Aminoethyl)-4-fluoro-N,N-dimethylaniline (CAS 1000551-95-0)
- 2-(2-Aminoethyl)-6-bromo-4-chlorophenol (CAS 1000575-19-8)
- N-(2-aminoethyl)-1-methyl-1H-pyrrole-2-carboxamide (CAS 1000931-92-9)
- n-(2-Aminoethyl)-1-methyl-4-(morpholine-4-sulfonyl)-1h-pyrrole-2-carboxamide (CAS 1000932-72-8)
- 4-[(2-aminoethyl)sulfamoyl]-1-methyl-1h-pyrrole-2-carboxamide (CAS 1000932-88-6)
- n-(2-Aminoethyl)-4,5-dibromo-1-methyl-1h-pyrrole-2-carboxamide (CAS 1000933-11-8)
Recommended Standards
- 4-Chloro-3-(chloromethyl)phenol (CAS 222623-28-1)
- Methyl 3-(2-{[2-(thiophene-2-amido)phenyl]sulfanyl}acetamido)thiophene-2-carboxylate (CAS 477887-58-4)
- 6-Methyl-3-(p-tolyl)-5,6-dihydroimidazo[2,1-b]thiazole (CAS 803626-65-5)
- (R)-2-Amino-2-(4-bromophenyl)ethanol hydrochloride (CAS 1916569-82-8)
- Bis(2-phenoxyethyl)ether (CAS 622-87-7)
- Morphine 6-Sulfate (CAS 23095-84-3)
- 2-(Difluoromethyl)-5-iodo-3-methylpyridine-4-carboxamide (CAS 1806022-94-5)
- 4-Bromo-1-ethxoy-2-ethylbenzene (CAS 749932-54-5)
- 7-(Trifluoromethyl)-1H-indazole (CAS 885694-00-8)
- HA Peptide (CAS 92000-76-5)
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