Orphenadrine USP Related Compound C CAS 10488-36-5
| CAS No. | 10488-36-5 |
| Molecular Formula | C17H21NO |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Orphenadrine USP Related Compound C (CAS 10488-36-5), a pharmacopoeial impurity reference standard (molecular formula C17H21NOHCl, MW 291.82 g/mol) used for the identification and quantification of trace impurities in APIs.
Orphenadrine USP Related Compound C (C17H21NOHCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H21NO HCl |
| Molecular Weight | 291.82 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1959 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Orphenadrine Standards
- Orphenadrine D3 Citrate (CAS 1185011-75-9)
- Orphenadrine-d (CAS 1309283-23-5)
- Orphenadrine EP Impurity C (CAS 17349-96-1)
- Orphenadrine EP Impurity E HCl (Orphenadrine USP Related Compound E HCl) (CAS 17630-53-4)
- Orphenadrine EP Impurity E (CAS 21945-86-8)
- Orphenadrine N-Oxide (CAS 29215-00-7)
- Orphenadrine Hydrochloride (CAS 341-69-5)
- Orphenadrine Impurity 3 (CAS 41870-52-4)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com