Phenoxymethylpenicillin EP Impurity E CAS 1049-84-9
| CAS No. | 1049-84-9 |
| Molecular Formula | C16H20N2O6S |
| Molecular Weight | 368.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Phenoxymethylpenicillin EP Impurity E.
CATO supplies Phenoxymethylpenicillin EP Impurity E (CAS 1049-84-9), a pharmacopoeial impurity reference standard (molecular formula C16H20N2O6S, MW 368.40 g/mol) used for the identification and quantification of trace impurities in APIs.
Phenoxymethylpenicillin EP Impurity E (C16H20N2O6S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H20N2O6S |
| Molecular Weight | 368.40 g/mol |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Phenoxymethylpenicillin Standards
- Phenoxymethylpenicillin EP Impurity D (CAS 20880-67-5)
- Phenoxymethylpenicillin Impurity 23 (CAS CATO-C4X-212623)
- Phenoxymethylpenicillin Impurity 20 (CAS CATO-C4X-212620)
- Phenoxymethylpenicillin Impurity 22 (CAS CATO-C4X-212622)
- Phenoxymethylpenicillin Impurity 19 (CAS CATO-C4X-212619)
- Phenoxymethylpenicillin Impurity 12 (CAS CATO-C4X-212612)
- Phenoxymethylpenicillin Impurity 16 (CAS CATO-C4X-212616)
- Phenoxymethylpenicillin EP Impurity F (2R,4S) (CAS 196701-54-9)
Recommended Standards
- Topiramate Impurity 34 (CAS CATO-C4X-176834)
- Pradofloxacin Impurity 1 (CAS CATO-C4X-25161)
- Topiramate Impurity 28 (CAS 53209-16-8)
- N-(6-((2-((Furan-2-ylmethyl)amino)-2-oxoethyl)thio)pyridazin-3-yl)benzamide (CAS 1021119-93-6)
- Vonoprazan Impurity 32 (CAS 2514742-82-4)
- Isoconazole nitrate EP Impurity C (CAS 22832-87-7)
- Brexpiprazole Impurity 156 (CAS CATO-C4X-1131156)
- (+)-Epibatidine (CAS 140111-52-0)
- 2,5-Dimethyl-4-(piperidin-1-yl)benzaldehyde (CAS 886501-24-2)
- 2-Chloro-N-(2-methyl-1-(thiophen-2-yl)propyl)acetamide (CAS 940271-64-7)
- Ethyl 3-cyano-2-hydroxy-6-isopropylisonicotinate (CAS 18924-80-6)
- Diethyl 2-(4-Methoxybenzyl)malonate (CAS 6335-37-1)
- 1-Cyclohexyl-1H-benzo[d]imidazol-2(3H)-one (CAS 100615-14-3)
- Glucagon receptor antagonists-2 (CAS 202917-18-8)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com