2-Fluoro-4-(2-methyl-1,3-thiazol-4-yl)phenol CAS 1049605-13-1

Purity 97%+In StockPharmaceutical Standards
CAS No.1049605-13-1
Molecular FormulaC10H8FNOS
Molecular Weight209.24 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Fluoro-4-(2-methyl-1,3-thiazol-4-yl)phenol CAS 1049605-13-1 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 209.24 g/mol gives 2-Fluoro-4-(2-methyl-1,3-thiazol-4-yl)phenol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-Fluoro-4-(2-methyl-1,3-thiazol-4-yl)phenol (CAS 1049605-13-1) is a high-purity analytical reference standard with the molecular formula C10H8FNOS and a molecular weight of 209.24 g/mol.

The molecular framework of 2-Fluoro-4-(2-methyl-1,3-thiazol-4-yl)phenol (C10H8FNOS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Fluoro-4-(2-methyl-1,3-thiazol-4-yl)phenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H8FNOS
Molecular Weight209.24 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1988
Halogen ContentF-containing
Nitrogen Atoms1
Sulfur Atoms1

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