2-(sec-butylamino)-N-[2-(trifluoromethyl)phenyl]acetamide hydrochloride CAS 1049751-46-3
| CAS No. | 1049751-46-3 |
| Molecular Formula | C13H17F3N2O |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-(sec-butylamino)-N-[2-(trifluoromethyl)phenyl]acetamide hydrochloride (C13H17F3N2OHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
2-(sec-butylamino)-N-[2-(trifluoromethyl)phenyl]acetamide hydrochloride (CAS 1049751-46-3) is a high-purity analytical reference standard with the molecular formula C13H17F3N2OHCl and a molecular weight of 310.74 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H17F3N2O HCl |
| Molecular Weight | 310.74 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related sec Standards
- 3-(sec-Butylamino)-N-methylpropanamide (CAS 1001346-14-0)
- 1,5-Bis(butylamino)anthracene-9,10-dione (CAS 100693-82-1)
- 2-(Tert-butylamino)-N-(2-methoxy-5-methylphenyl)acetamide (CAS 1007821-96-6)
- 2-((tert-Butylamino)methyl)-5-((7-chloroquinolin-4-yl)amino)phenol dihydrochloride (CAS 1010411-21-8)
- 2-((5-(Butylamino)-1,3,4-thiadiazol-2-yl)thio)-N-(1-cyanocyclohexyl)-N-methylacetamide (CAS 1012170-55-6)
- 2-((Sec-butylamino)methyl)-4,6-dichlorophenol (CAS 101583-48-6)
- 2-(tert-Butylamino)isonicotinic acid (CAS 1019387-62-2)
- 6-(Tert-butylamino)nicotinic acid (CAS 1019387-69-9)
Recommended Standards
- 2-(2,6-Difluoro-benzoylamino)-3-methyl-butyric acid (CAS 1396972-19-2)
- 4-boronothiophene-2-carboxylic acid (CAS 913835-91-3)
- 2-(2-Methylpyridin-3-yl)oxyethanol (CAS 313656-68-7)
- W-15 (CAS 93100-99-3)
- (1S,3S)-3-methoxycyclohexan-1-ol (CAS 1932152-93-6)
- Ethyl 2-(4-amino-2-nitrophenyl)acetate (CAS 108274-41-5)
- Metosulam-5-hydroxy (CAS 156759-52-3)
- (4-Piperidin-4-ylphenyl)methanol;hydrochloride (CAS 1187927-60-1)
- 3,5-Dibromo-2,6-difluorobenzoic acid (CAS 28314-84-3)
- Osteoblast Activating Peptide (mouse, rat) (H-7262.0500) (CAS 1222950-80-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com