2-(2,3-Dimethoxyphenyl)-2-(1H-indol-3-yl)ethan-1-amine hydrochloride CAS 1049752-42-2
| CAS No. | 1049752-42-2 |
| Molecular Formula | C18H20N2O2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(2,3-Dimethoxyphenyl)-2-(1H-indol-3-yl)ethan-1-amine hydrochloride (C18H20N2O2HCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
2-(2,3-Dimethoxyphenyl)-2-(1H-indol-3-yl)ethan-1-amine hydrochloride (CAS 1049752-42-2), molecular formula C18H20N2O2HCl and molecular weight 332.83 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H20N2O2 HCl |
| Molecular Weight | 332.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dimethoxyphenyl Standards
- [(2,3-dimethoxyphenyl)methyl](ethyl)amine (CAS 100054-84-0)
- 5-(3,5-Dimethoxyphenyl)-3-oxopentanenitrile (CAS 1000895-54-4)
- 6-(3,5-Dimethoxyphenyl)-3-(4-fluorophenyl)-1H-pyrazolo[3,4-b]pyridine (CAS 1001083-74-4)
- 3-(2,5-Dimethoxyphenyl)propanoyl chloride (CAS 100126-94-1)
- 2-(3,5-Dimethoxyphenyl)morpholine (CAS 1001940-37-9)
- (2E)-1-(2,4-Dimethoxyphenyl)-3-[4-(propan-2-yl)phenyl]prop-2-en-1-one (CAS 1002460-32-3)
- (2E)-1-(2,4-Dimethoxyphenyl)-3-(5-methylthiophen-2-yl)prop-2-en-1-one (CAS 1002460-75-4)
- 1-(3,4-Dimethoxyphenyl)butan-1-amine hydrochloride (CAS 100252-51-5)
Recommended Standards
- AH 11110 (CAS 179388-65-9)
- 4-(4,5-Dimethyl-1H-imidazol-1-yl)-2-methyl-6-(piperazin-1-yl)pyrimidine (CAS 1706454-58-1)
- 4-(tert-Butyl)-2-(4-fluorophenyl)pyridine (CAS 1246851-68-2)
- 4-((5,6-Dimethylthieno[2,3-d]pyrimidin-4-yl)amino)phenol (CAS 799800-65-0)
- Ethyl 2-((6,7-difluorobenzo[d]oxazol-2-yl)thio)acetate (CAS 1071369-10-2)
- Opicapone impurity 70 (CAS CATO-C4X-240470)
- N1-((2-Bromopyridin-4-yl)methyl)-N1-isopropylethane-1,2-diamine (CAS 1353960-30-1)
- 3-(Trifluoromethyl)isonicotinic Acid (CAS 590371-38-3)
- 878905-11-4 CTK5F9104 L-Norleucine,N-[(1,1-dimethylethoxy)carbonyl]-6-[(methylsulfonyl)oxy]-, 1,1-dimethylethylester (CAS 878905-11-4)
- Semaglutide Impurity 144 (CAS 394210-59-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com