4-(Chloromethyl)-2-[4-(propan-2-yl)phenyl]-1,3-thiazole hydrochloride CAS 1049790-37-5
| CAS No. | 1049790-37-5 |
| Molecular Formula | C13H14ClNS |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-(Chloromethyl)-2-[4-(propan-2-yl)phenyl]-1,3-thiazole hydrochloride (C13H14ClNSHCl) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
4-(Chloromethyl)-2-[4-(propan-2-yl)phenyl]-1,3-thiazole hydrochloride (CAS 1049790-37-5), molecular formula C13H14ClNSHCl and molecular weight 288.23 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-(Chloromethyl)-2-[4-(propan-2-yl)phenyl]-1,3-thiazole hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H14ClNS HCl |
| Molecular Weight | 288.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloromethyl Standards
- 7-(Chloromethyl)-3-methyl-5H-thiazolo[3,2-a]pyrimidin-5-one (CAS 100003-81-4)
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- 7-(Chloromethyl)-3-(4-chlorophenyl)-5H-thiazolo[3,2-a]pyrimidin-5-one (CAS 100003-85-8)
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Recommended Standards
- 5-acetyl-2-chlorobenzene-1-sulfonamide (CAS 2350-44-9)
- [3-Fluoro-4-(2,2,2-trifluoroethoxy)benzyl]methylamine (CAS 1095179-02-4)
- (2R,3S,4S,5R)-2-(hydroxymethyl)-6-(octyloxy)tetrahydro-2H-pyran-3,4,5-triol (CAS 41444-50-2)
- 3-(Isoxazol-3-yl)pyrazin-2-ol (CAS 81411-75-8)
- 2-(4-Bromophenyl)-3h-imidazo[4,5-b]pyridine (CAS 75007-86-2)
- 2-Phenoxy-N-(pyridin-3-yl)acetamide (CAS 25288-46-4)
- 4-(1,3,5-Trimethyl-1H-pyrazol-4-yl)butan-2-one (CAS 1021910-54-2)
- 4-bromo-5-fluoro-2-methoxybenzene-1-sulfonyl chloride (CAS 1443979-74-5)
- 4-(Dimethylamino)-2-(3,5-dimethylphenyl)isoindoline-1,3-dione (CAS 651733-73-2)
- Fibrinogen-Binding Inhibitor Peptide (CAS 89105-94-2)
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