DMT-2′O-TBDMS-rA (bz) phosphoramidite CAS 104992-55-4

Purity 97%+In StockPharmaceutical Standards
CAS No.104992-55-4
Molecular FormulaC53H98N7O8PSi
Molecular Weight1020.45 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

DMT-2′O-TBDMS-rA (bz) phosphoramidite CAS 104992-55-4 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

DMT-2′O-TBDMS-rA (bz) phosphoramidite (CAS 104992-55-4), molecular formula C53H98N7O8PSi and molecular weight 1020.45 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of DMT-2′O-TBDMS-rA (bz) phosphoramidite (C53H98N7O8PSi) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC53H98N7O8PSi
Molecular Weight1020.45 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)8.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1986
Nitrogen Atoms7

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