(2S,4R)-4-(2-Fluorobenzyl)pyrrolidine-2-carboxylic acid CAS 1049977-87-8
| CAS No. | 1049977-87-8 |
| Molecular Formula | C12H14FNO2 |
| Molecular Weight | 223.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 223.24 g/mol gives (2S,4R)-4-(2-Fluorobenzyl)pyrrolidine-2-carboxylic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(2S,4R)-4-(2-Fluorobenzyl)pyrrolidine-2-carboxylic acid (CAS 1049977-87-8), molecular formula C12H14FNO2 and molecular weight 223.24 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, (2S,4R)-4-(2-Fluorobenzyl)pyrrolidine-2-carboxylic acid (C12H14FNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 223.24 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H14FNO2 |
| Molecular Weight | 223.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- (2-Fluorobenzyl)proline (CAS 1038747-37-3)
- (2S,4R)-4-(4-Fluorobenzyl)pyrrolidine-2-carboxylic acid (CAS 1049977-93-6)
- 1-[(4-fluorophenyl)methyl]pyrrolidine-2-carboxylic acid (CAS 1026725-31-4)
- (2-Fluoro-phenyl)-(4-hydroxy-piperi (CAS 1082804-68-9)
- tert-Butyl 4-(2-(methylamino)ethyl)piperidine-1-carboxylate (CAS 896103-62-1)
- 1-piperidin-4-yl-1H-benzimidazole,HCl (CAS 83763-11-5)
- 5-(2-Chlorophenyl)pyrazin-2-amine (CAS 71553-78-1)
- n-(2-Ethoxyphenyl)-2-((2-nitropyridin-3-yl)oxy)acetamide (CAS 763098-42-6)
- 4-(5-Chloro-1H-1,2,4-triazol-3-yl)phenol (CAS 1315346-26-9)
- 4,5-Dimethyl-N-(pyridin-3-ylmethyl)-1,3-benzothiazol-2-amine (CAS 1105192-44-6)
- 3,6-bis(fluoranyl)-4-(trifluoromethyl)pyridin-2-amine 3,6-difluoro-4-(trifluoromethyl)-2-pyridinamine 675602-89-8 A835813 (CAS 675602-89-8)
- (R)-tert-Butyl 3-(2-bromobenzylamino)piperidine-1-carboxylate (CAS 1286209-28-6)
- 1-Allyl-3-(3-hydroxybenzyl)urea (CAS 1311958-80-1)
- Antiarrhythmic peptide (cattle atrium) (CAS 81771-37-1)
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