(2S,4R)-4-(3-Chlorobenzyl)pyrrolidine-2-carboxylic acid CAS 1049978-11-1
| CAS No. | 1049978-11-1 |
| Molecular Formula | C12H14ClNO2 |
| Molecular Weight | 239.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), (2S,4R)-4-(3-Chlorobenzyl)pyrrolidine-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies (2S,4R)-4-(3-Chlorobenzyl)pyrrolidine-2-carboxylic acid (CAS 1049978-11-1), a certified reference material (molecular formula C12H14ClNO2, MW 239.70 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, (2S,4R)-4-(3-Chlorobenzyl)pyrrolidine-2-carboxylic acid is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 239.70 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H14ClNO2 |
| Molecular Weight | 239.70 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- (2S,4R)-4-(2-Chlorobenzyl)pyrrolidine-2-carboxylic acid (CAS 1049978-05-3)
- (2S,4R)-4-(4-Chlorobenzyl)pyrrolidine-2-carboxylic acid (CAS 1049978-20-2)
- (4-Aminopiperidin-1-yl)(2-chloropyridin-4-yl)methanone (CAS 1027011-05-7)
- N-[(3-chlorophenyl)methyl]-N-methyl-3-oxobutanamide (CAS 105964-54-3)
- 2-Formyl-6-(4-trifluoromethylphenyl)phenol (CAS 1261995-54-3)
- 2-(3-(Difluoromethyl)phenoxy)ethan-1-amine (CAS 1897638-12-8)
- 3-Methyl-3-phenylpentane-1,5-diol (CAS 84100-46-9)
- 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-5-methyluridine (CAS 133324-02-4)
- 3-Amino-3-methyl-1-pyrrolidino-1-butanone Hydrochloride (CAS 1246471-46-4)
- 5-Amino-1-benzyl-N-(4-fluoro-2-methylphenyl)-1H-1,2,3-triazole-4-carboxamide (CAS 900013-25-4)
- 3,4-Dibromopicolinic acid (CAS 1803786-06-2)
- N-(4-chloro-2-methylphenyl)tetrahydro-2H-pyran-4-amine (CAS 1157010-35-9)
- 3-Acetyl-5-chlorobenzonitrile (CAS 1393581-95-7)
- (Pro3)-Gastric Inhibitory Polypeptide (human) trifluoroacetate salt (CAS 299898-52-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com