2-(4-Methoxy-2-nitrophenyl)acetonitrile CAS 105003-90-5
| CAS No. | 105003-90-5 |
| Molecular Formula | C9H8N2O3 |
| Molecular Weight | 192.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2-(4-Methoxy-2-nitrophenyl)acetonitrile (CAS 105003-90-5), molecular formula C9H8N2O3 and molecular weight 192.17 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(4-Methoxy-2-nitrophenyl)acetonitrile (C9H8N2O3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures 2-(4-Methoxy-2-nitrophenyl)acetonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H8N2O3 |
| Molecular Weight | 192.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Nitrogen Atoms | 2 |
Related Methoxy Standards
- 4-Methoxy-1H-pyrrolo[3,2-c]pyridine-3-carboxylic acid (CAS 1000341-34-3)
- 2-(3-Methoxy-4-nitrophenyl)acetonitrile (CAS 104103-16-4)
- 5-Methoxy-7-nitro-1H-indole (CAS 10553-10-3)
- 5-Methoxy-2-methyl-3-nitrobenzonitrile (CAS 1082040-58-1)
- 6-Methoxy-1H-indazole-5-carboxylic Acid (CAS 1082041-60-8)
- 2-(3-methoxy-2-nitrophenyl)acetonitrile (CAS 111795-89-2)
- 4-Methoxy-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid (CAS 1190311-20-6)
- 6-Methoxy-1H-pyrrolo[3,2-c]pyridine-3-carboxylic acid (CAS 1190313-17-7)
Recommended Standards
- 7-Ethyl-[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylic acid (CAS 1049606-50-9)
- 1-(2-Cyanoethyl)-2-oxo-1,2-dihydropyridine-3-carboxylic acid (CAS 1053658-31-3)
- N-(2-nitrophenyl)prop-2-enamide (CAS 104373-98-0)
- 3-Methoxybenzofuran-2-carboxylic acid (CAS 104315-56-2)
- N-(5-(4-Aminophenoxy)pentyl)-2,2-dichloroacetamide (CAS 101264-04-4)
- 2-Oxo-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-4'-carbonitrile hydrochloride (CAS 1423027-48-8)
- 9-([1,1'-Biphenyl]-3-yl)-3-broMo-9H-carbazole (CAS 1428551-28-3)
- 2,6-Diamino-4-(difluoromethyl)pyridin-3-ol (CAS 1803669-90-0)
- Biotin Hydrazide (CAS 66640-86-6)
- 3-Chloro-N-(3-chloro-4-methylphenyl)propanamide (CAS 51318-77-5)
- (5-Amino-2-methoxyphenyl)boronic acid (CAS 948592-70-9)
- 3-[(5-ethyl-1,3,4-thiadiazol-2-yl)carbamoyl]propanoic acid (CAS 79888-40-7)
- Nintedanib Impurity 180 (CAS 2117628-65-4 (free base))
- Liraglutide(3-31)TFA Salt (CAS CATO-C4X-19921)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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