Ethyl 2-bromo-2-(5-chloro-2-methoxyphenyl)acetate CAS 1050481-79-2
| CAS No. | 1050481-79-2 |
| Molecular Formula | C11H12BrClO3 |
| Molecular Weight | 307.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Ethyl 2-bromo-2-(5-chloro-2-methoxyphenyl)acetate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Ethyl 2-bromo-2-(5-chloro-2-methoxyphenyl)acetate (CAS 1050481-79-2), molecular formula C11H12BrClO3 and molecular weight 307.57 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Ethyl 2-bromo-2-(5-chloro-2-methoxyphenyl)acetate (C11H12BrClO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H12BrClO3 |
| Molecular Weight | 307.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl/Br-containing |
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- Phenelzine D5 HCl salt (CAS CATO-C3D-262645)
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- 2-(Aminomethyl)-4-bromo-5-chloroaniline (CAS 1379346-13-0)
- 1-(3,4-Dimethoxyphenyl)propane-1,3-diol (CAS 76788-37-9)
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- 3-Isopropoxyazetidine (CAS 871791-79-6)
- Peptide 431 (CAS CATO-CPTD788431)
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