Trans-benzyl 3-((tert-butoxycarbonyl)amino)-4-fluoropiperidine-1-carboxylate CAS 1052713-40-2
| CAS No. | 1052713-40-2 |
| Molecular Formula | C18H25FN2O4 |
| Molecular Weight | 352.40 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Trans-benzyl 3-((tert-butoxycarbonyl)amino)-4-fluoropiperidine-1-carboxylate (CAS 1052713-40-2) is a high-purity analytical reference standard with the molecular formula C18H25FN2O4 and a molecular weight of 352.40 g/mol.
Trans-benzyl 3-((tert-butoxycarbonyl)amino)-4-fluoropiperidine-1-carboxylate (C18H25FN2O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H25FN2O4 |
| Molecular Weight | 352.40 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- Benzyl (3R,4R)-3-((tert-butoxycarbonyl)amino)-4-fluoropiperidine-1-carboxylate (CAS 1052713-38-8)
- 2,5-Dibromo-4-fluorobenzenesulfonyl chloride (CAS 1123306-72-8)
- 2,4-Dibromo-5-fluorobenzenesulfonyl chloride (CAS 1000578-09-5)
- 1-tert-Butyl 2-methyl (2S,4S)-4-[(2-fluorobenzyl)-amino]pyrrolidine-1,2-dicarboxylate (CAS 1186652-57-2)
- 2-(2-Furyl)alanine (CAS 2644-43-1)
- (R)-N-(1-Phenylethyl)acetamide (CAS 36283-44-0)
- 1-(4-(Hydroxymethyl)phenyl)naphthalen-2-ol (CAS 1365968-64-4)
- 3-(6-Methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)propanoic acid (CAS 215785-22-1)
- Fmoc-S-3-amino-4-(4-tert-butylphenyl)-butyric acid (CAS 403661-86-9)
- 4-Bromo-5-nitro-2-(trifluoromethyl)pyridine (CAS 1695674-38-4)
- 4-Ethoxy-3-methylbenzoyl chloride (CAS 91900-26-4)
- Cyclobutyl 3,5-dimethylphenyl ketone (CAS 898790-79-9)
- 2-Benzyloxy-3-nitrophenylamine hydrochloride (CAS 847657-55-0)
- Semaglutide impurity 68 (CAS CATO-C4X-222668)
Why CATO?
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