Ramelteon Impurity 10 HCl CAS 1053239-39-6
| CAS No. | 1053239-39-6 |
| Molecular Formula | C13H17NO |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Ramelteon Impurity 10 HCl (C13H17NOHCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Ramelteon Impurity 10 HCl (CAS 1053239-39-6) is a certified pharmaceutical impurity reference standard with the molecular formula C13H17NOHCl and a molecular weight of 239.74 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H17NO HCl |
| Molecular Weight | 239.74 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Ramelteon Standards
- Ramelteon Impurity 42 (CAS 1053239-38-5)
- Ramelteon Imputiry 17 (CAS 1092484-10-0)
- Ramelteon Impurity 20 (CAS 1092507-02-2)
- Ramelteon Impurity 21 (CAS 1092507-03-3)
- Ramelteon Imputiry 18 (CAS 1092507-07-7)
- Ramelteon Impurity 25 HCI (CAS 1174496-11-7)
- rac Ramelteon-d3 (CAS 1185146-24-0)
- Ramelteon Impurity 56 (CAS 1185516-79-3)
Recommended Standards
- Urapidil Impurity 68 (CAS 1703052-28-1)
- Ampicillin Impurity 60 (CAS CATO-C4X-144360)
- Maxacalcitol Impurity 44 (CAS 227961-42-4)
- Tris(allyloxy)methane (CAS 16754-50-0)
- 4-Bromo-2-iodo-1-(trifluoromethoxy)benzene (CAS 154065-33-5)
- Nalmefene Impurity 12 (CAS 176220-84-1)
- 4'-(Methylsulfanyl)[1,1'-biphenyl]-4-carbonitrile (CAS 130373-85-2)
- 1-(2-(Ethylamino)pyrimidin-4-yl)piperidin-4-ol (CAS 1206969-02-9)
- (1,2,3,4-Tetrahydronaphthalen-1-yl)urea (CAS 58490-97-4)
- [14-31]-Semaglutide (CAS CATO-C4X-2226262)
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